Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein. (Q53619988)

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English	Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.	scientific article

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scholarly article

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein. (English)

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

David L Bourdet

1

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

Dhiren R Thakker

2

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

publication date

8 June 2006

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

Pharmaceutical Research

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

23

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

1165-1177

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

6

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

Cardiac and gastric effects of histamine H2 receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-0251-4

21 January 2018

Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-0251-4

21 January 2018

Common characteristics for Na+-dependent sugar transport in Caco-2 cells and human fetal colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cimetidine transport in brush-border membrane vesicles from rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saturable transport of H2-antagonists ranitidine and famotidine across Caco-2 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of HT29-18-C1 and Caco-2 cell lines as models for studying intestinal paracellular drug absorption.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of paracellular absorption of cimetidine and 5-aminosalicylate in rat intestine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetry of plasma membrane lipid order in Madin-Darby Canine Kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a novel cationic drug transporter in human retinal pigment epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of MPP+ secretion across human intestinal Caco-2 cell monolayers: role of P-glycoprotein and a novel Na(+)-dependent organic cation transport mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory transport of ranitidine and famotidine across Caco-2 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional gastrointestinal absorption of ranitidine in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrier-mediated active transport of histamine H2 receptor antagonists, cimetidine and nizatidine, into isolated rat hepatocytes: contribution of type I system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organic cation transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diphenhydramine transport by pH-dependent tertiary amine transport system in Caco-2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of intracellular pH in proximal tubules of avian long-looped mammalian-type nephrons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of gallbladder tight junction cation-selective channels by 2,4,6-triaminopyrimidinium (TAP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of passive permeability on apparent P-glycoprotein kinetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisubstrates: substances that interact with renal contraluminal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imidazoles, thiazoles, guanidines and hydrazines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transepithelial transport of diphenhydramine across monolayers of the human intestinal epithelial cell line Caco-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cimetidine uptake and interactions with cationic drugs in freshly isolated proximal tubular cells of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling of P-glycoprotein-involved epithelial drug transport in MDCK cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic properties of histamine H2-receptor antagonists. Relationship between intrinsic potency and effective plasma concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of intestinal absorption of ranitidine and ondansetron: transport across Caco-2 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and functional expression of a human liver organic cation transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16741655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-006-0251-4

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16741655

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