Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome. (Q54136053)

25 May 2018

title

Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome. (English)

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25 May 2018

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Imamura T

1

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Haruta T

2

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Takata Y

3

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Usui I

4

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Iwata M

5

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Ishihara H

6

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Ishiki M

7

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Ishibashi O

8

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Ueno E

9

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Sasaoka T

10

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Kobayashi M

11

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language of work or name

English

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publication date

1 May 1998

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25 May 2018

Journal of Biological Chemistry

published in

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25 May 2018

volume

273

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25 May 2018

issue

18

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25 May 2018

page(s)

11183-11188

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25 May 2018

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

cites work

1 reference

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The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

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Activation of glucose transport by a natural mutation in the human insulin receptor

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Leu 193 mutation in the cysteine rich region of the insulin receptor inhibits the cleavage of the insulin receptor precursor but not insulin binding

21 January 2018

1 reference

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A leucine to proline mutation at position 233 in the insulin receptor inhibits cleavage of the proreceptor and transport to the cell surface

21 January 2018

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Selective protein degradation: a journey's end within the proteasome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

21 January 2018

1 reference

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Proteasomes: multicatalytic proteinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Transfection of cDNA with G----T point mutation at the cleavage site of insulin receptors to COS 7 cells

21 January 2018

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An extracellular domain of the beta subunit is essential for processing, transport and kinase activity of insulin receptor

21 January 2018

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Human insulin-receptor gene. Partial sequence and amplification of exons by polymerase chain reaction

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Protein folding in the cell

21 January 2018

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Molecular chaperones in cellular protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Hsp70 family molecular chaperones and mutant insulin receptor: differential binding specificities of BiP and Hsp70/Hsc70 determines accumulation or degradation of insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Degradation of CFTR by the ubiquitin-proteasome pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Isolation of Hsp90 mutants by screening for decreased steroid receptor function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Protein folding and the regulation of signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Ala1048-->Asp mutation in the kinase domain of insulin receptor causes defective kinase activity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

Functional properties of a naturally occurring Trp1200----Ser1200 mutation of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.18.11183

21 January 2018

Identifiers

DOI

10.1074/JBC.273.18.11183

1 reference

25 May 2018

1 reference

25 May 2018