A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1. (Q54343459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947582%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1 (English)

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20 March 2020

11

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20 March 2020

author name string

Hong-Mei Wang

1

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20 March 2020

Jun-Hong Dong

2

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20 March 2020

Qing Li

3

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20 March 2020

Qiaoxia Hu

4

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20 March 2020

Shang-Lei Ning

5

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20 March 2020

Wenshuai Zheng

6

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20 March 2020

Min Cui

7

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20 March 2020

Tian-Sheng Chen

8

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20 March 2020

Xin Xie

9

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20 March 2020

Jin-Peng Sun

10

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20 March 2020

publication date

20 June 2014

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20 March 2020

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20 March 2020

volume

57

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20 March 2020

issue

9

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20 March 2020

page(s)

1899-1910

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https://scigraph.springernature.com/pub.10.1007/s00125-014-3290-0

20 March 2020

exact match

0 references

cites work

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function

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Immunoneutralization of somatostatin, insulin, and glucagon causes alterations in islet cell secretion in the isolated perfused human pancreas

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Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas

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Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes.

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GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells

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Pax6 and Pdx1 form a functional complex on the rat somatostatin gene upstream enhancer

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24947582

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-like, and alpha-CBF-like transcription factors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24947582

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of somatostatin gene transcription by cAMP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24947582