Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. (Q54412464)

29 May 2018

title

Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. (English)

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29 May 2018

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11

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Michel Mittelbronn

9

object named as

Michel Mittelbronn

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10

Stefan Rutkowski

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author name string

Denis Faoro

1

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André O von Bueren

2

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Tarek Shalaby

3

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Davide Sciuscio

4

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Marie-Louise Hürlimann

5

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Lucia Arnold

6

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Nicolas U Gerber

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Johannes Haybaeck

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Michael A Grotzer

12

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publication date

5 September 2010

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Journal of Neuro-Oncology

published in

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volume

103

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issue

1

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page(s)

59-69

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Alternative treatments for childhood brain tumors

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MGMT gene silencing and benefit from temozolomide in glioblastoma

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Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

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Intercellular heterogeneity of expression of the MGMT DNA repair gene in pediatric medulloblastoma

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Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.

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Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

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Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1

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Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91.

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12 December 2020

Expression of O6-methylguanine-DNA methyltransferase in six human medulloblastoma cell lines

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12 December 2020

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

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Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin

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12 December 2020

10.1007/S11060-010-0366-7

Identifiers

DOI

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29 May 2018

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29 May 2018