Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies. (Q54442651)

29 May 2018

title

Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies. (English)

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29 May 2018

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Kucherlapati M

1

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29 May 2018

Nguyen A

2

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29 May 2018

Kuraguchi M

3

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29 May 2018

Yang K

4

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29 May 2018

Fan K

5

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29 May 2018

Bronson R

6

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29 May 2018

Wei K

7

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29 May 2018

Lipkin M

8

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29 May 2018

Edelmann W

9

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29 May 2018

Kucherlapati R

10

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29 May 2018

language of work or name

English

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publication date

23 April 2007

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29 May 2018

published in

Oncogene

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29 May 2018

volume

26

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29 May 2018

issue

43

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29 May 2018

page(s)

6297-6306

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29 May 2018

The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae

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Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability

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A defined human system that supports bidirectional mismatch-provoked excision

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Loss of DNA mismatch repair function and cancer predisposition in the mouse: animal models for human hereditary nonpolyposis colorectal cancer

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A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

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7 January 2021

Loss of adenomatous polyposis coli gene function disrupts thymic development

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Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

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7 January 2021

Molecular interactions of human Exo1 with DNA

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The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

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Flap endonuclease 1: a central component of DNA metabolism

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Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

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Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1

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7 January 2021

The interaction of DNA mismatch repair proteins with human exonuclease I

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7 January 2021

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

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7 January 2021

Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae

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7 January 2021

EXO1-A multi-tasking eukaryotic nuclease.

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Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

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7 January 2021

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

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7 January 2021

Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms

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7 January 2021

Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210453

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29 May 2018

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29 May 2018