Studies of the biological properties of human beta-defensin 1. (Q54452869)

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21 December 2019

title

Studies of the biological properties of human beta-defensin 1 (English)

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21 December 2019

2

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1

Marzena Pazgier

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21 December 2019

author name string

David M Hoover

series ordinal

3

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21 December 2019

Jacek Lubkowski

series ordinal

4

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21 December 2019

language of work or name

English

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publication date

27 October 2006

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Journal of Biological Chemistry

21 December 2019

published in

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21 December 2019

volume

282

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21 December 2019

issue

3

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21 December 2019

page(s)

1819-1829

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Functions of antimicrobial peptides in host defense and immunity

21 December 2019

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Defensins: antimicrobial peptides of innate immunity

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Theta-defensins: cyclic antimicrobial peptides produced by binary ligation of truncated alpha-defensins

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Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction

21 January 2018

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Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

21 January 2018

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A peptide antibiotic from human skin

21 January 2018

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Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

21 January 2018

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Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity

21 January 2018

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Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins

21 January 2018

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Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

21 January 2018

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Discovery of five conserved beta -defensin gene clusters using a computational search strategy

21 January 2018

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Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

21 January 2018

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

21 January 2018

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Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils

21 January 2018

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Human beta-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection.

21 January 2018

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Upregulated expression of human β defensin-1 and -3 mRNA during differentiation of keratinocyte immortalized cell lines, HaCaT and PHK16-0b

21 January 2018

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Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors

21 January 2018

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Beta-defensin 126 on the cell surface protects sperm from immunorecognition and binding of anti-sperm antibodies.

21 January 2018

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Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

21 January 2018

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Human airway epithelia express a beta-defensin

21 January 2018

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The CC chemokine CCL20 and its receptor CCR6.

21 January 2018

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STRL22 is a receptor for the CC chemokine MIP-3alpha

21 January 2018

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Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3alpha

21 January 2018

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The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

21 January 2018

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NMR solution structure of murine CCL20/MIP-3alpha, a chemokine that specifically chemoattracts immature dendritic cells and lymphocytes through its highly specific interaction with the beta-chemokine receptor CCR6

21 January 2018

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Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

21 January 2018

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Expression and purification of recombinant human alpha-defensins in Escherichia coli.

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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AMoRe: an automated package for molecular replacement

21 January 2018

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The structure of human beta-defensin-1: new insights into structural properties of beta-defensins

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Efficient anisotropic refinement of macromolecular structures using FFT

21 January 2018

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Neutrophil defensins: purification, characterization, and antimicrobial testing

21 January 2018

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Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity

21 January 2018

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Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

21 January 2018

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The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment

21 January 2018

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Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity

21 January 2018

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The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus

21 January 2018

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Antimicrobial characterization of human beta-defensin 3 derivatives

21 January 2018

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Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity

21 January 2018

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Antibacterial activities and conformations of bovine beta-defensin BNBD-12 and analogs:structural and disulfide bridge requirements for activity

21 January 2018

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Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions

21 January 2018

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21 January 2018

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Single disulfide and linear analogues corresponding to the carboxy-terminal segment of bovine beta-defensin-2: effects of introducing the beta-hairpin nucleating sequence d-pro-gly on antibacterial activity and Biophysical properties.

21 January 2018

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Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

21 January 2018

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Mammalian defensins: structures and mechanism of antibiotic activity.

21 January 2018

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Channel-forming membrane permeabilization by an antibacterial protein, sapecin: determination of membrane-buried and oligomerization surfaces by NMR.

21 January 2018

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Effects of positively selected sequence variations in human and Macaca fascicularis beta-defensins 2 on antimicrobial activity.

21 January 2018

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Mutating the four extracellular cysteines in the chemokine receptor CCR6 reveals their differing roles in receptor trafficking, ligand binding, and signaling

21 January 2018

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Molecular characterization of CCR6: involvement of multiple domains in ligand binding and receptor signaling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M607210200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17071614%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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