Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells. (Q54517713)

30 May 2018

title

Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells. (English)

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30 May 2018

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Hrvoje Lalic

1

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30 May 2018

Vesna Lukinovic-Skudar

series ordinal

2

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30 May 2018

Hrvoje Banfic

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3

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30 May 2018

Dora Visnjic

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4

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30 May 2018

publication date

21 May 2012

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30 May 2018

published in

Leukemia & Lymphoma

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30 May 2018

volume

53

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30 May 2018

issue

11

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30 May 2018

page(s)

2253-2261

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30 May 2018

Targeting mTOR for the treatment of AML. New agents and new directions

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Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

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Survival of acute myeloid leukemia cells requires PI3 kinase activation

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Antileukemic activity of rapamycin in acute myeloid leukemia.

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Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.

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Targeting the translational machinery as a novel treatment strategy for hematologic malignancies

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Differentiation therapy of acute myeloid leukemia: past, present and future

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Mechanisms of resistance to apoptosis in human AML blasts: the role of differentiation-induced perturbations of cell-cycle checkpoints.

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The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells.

21 January 2018

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Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells

21 January 2018

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Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo

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Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide

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Role of the p70 S6 kinase cascade in neutrophilic differentiation and proliferation of HL-60 cells-a study of transferrin receptor-positive and -negative cells obtained from dimethyl sulfoxide- or retinoic acid-treated HL-60 cells

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Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization.

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Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation

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The role of the nuclear Akt activation and Akt inhibitors in all-trans-retinoic acid-differentiated HL-60 cells

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Combined inhibition of PI3K and mTOR exerts synergistic antiproliferative effect, but diminishes differentiative properties of rapamycin in acute myeloid leukemia cells.

21 January 2018

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Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

21 January 2018

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Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors

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Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

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Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation

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Ribosomal p70S6K basal activity increases upon induction of differentiation of myelomonocytic leukemic cell lines HL60, AML14 and MPD

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Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells

21 January 2018

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Neutral sphingomyelinase-2 mediates growth arrest by retinoic acid through modulation of ribosomal S6 kinase

21 January 2018

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Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells

21 January 2018

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Acquisition of potential N-glycosylation sites in the immunoglobulin variable region by somatic mutation is a distinctive feature of follicular lymphoma.

21 January 2018

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Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation

21 January 2018

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10.3109/10428194.2012.684351

21 January 2018

Identifiers

DOI

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30 May 2018

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30 May 2018