BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases. (Q54528429)

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23 January 2020

title

BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases (English)

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23 January 2020

5

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author name string

Zsolt Sarszegi

1

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23 January 2020

Eszter Bognar

2

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23 January 2020

Balazs Gaszner

3

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23 January 2020

Attila Kónyi

4

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23 January 2020

Balazs Sumegi

6

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23 January 2020

Zoltan Berente

7

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publication date

14 February 2012

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Molecular and Cellular Biochemistry

23 January 2020

published in

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volume

365

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issue

1-2

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23 January 2020

page(s)

129-137

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https://scigraph.springernature.com/pub.10.1007/s11010-012-1252-8

23 January 2020

exact match

0 references

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Role of poly(ADP-ribose) polymerase activity in imatinib mesylate-induced cell death

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Cardioprotective effects of poly(ADP-ribose) polymerase inhibition

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Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors

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Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: a proof of concept randomized double-blind clinical trial

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Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone

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STRESS signaling pathways that modulate cardiac myocyte apoptosis

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Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress.

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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Akt activation induced by an antioxidant compound during ischemia-reperfusion

21 January 2018

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BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury

21 January 2018

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BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity

21 January 2018

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BGP-15, a hydroximic acid derivative, protects against cisplatin- or taxol-induced peripheral neuropathy in rats

21 January 2018

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Beneficial effect of the insulin sensitizer (HSP inducer) BGP-15 on olanzapine-induced metabolic disorders

21 January 2018

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PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway.

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The role of Ca(2+) signaling in the coordination of mitochondrial ATP production with cardiac work

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Oxidative stress and left ventricular remodelling after myocardial infarction

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Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

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Salvage of ischemic myocardium: a focus on JNK.

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12 December 2020

Myocardial protection by selective poly(ADP-ribose) polymerase inhibitors.

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12 December 2020

Mitochondrially targeted antioxidants for the treatment of cardiovascular diseases

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12 December 2020

Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system.

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12 December 2020

BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymerase

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12 December 2020

Altered signalling and gene expression associated with the immune system and the inflammatory response in obesity

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12 December 2020

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10.1007/S11010-012-1252-8

Identifiers

DOI

1 reference

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23 January 2020

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