Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. (Q54545005)

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English	Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

1 reference

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author name string

Hong-Quan Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

Yu-Xia Xu

2

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

Cui-Qing Zhu

3

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

publication date

7 December 2011

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

Neurotoxicity Research

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

21

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

4

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

368-378

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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A novel kavalactone derivative protects against H2O2-induced PC12 cell death via Nrf2/ARE activation

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Nrf2-Keap1 defines a physiologically important stress response mechanism

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells.

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Dietary intake of antioxidants and risk of Alzheimer disease

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Acteoside protects human neuroblastoma SH-SY5Y cells against beta-amyloid-induced cell injury

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Chronic restraint stress alters the expression and distribution of phosphorylated tau and MAP2 in cortex and hippocampus of rat brain

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by beta-amyloid peptides 25-35 in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Hydrogen peroxide mediates amyloid beta protein toxicity

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Overexpression of heme oxygenase-1 protects dopaminergic neurons against 1-methyl-4-phenylpyridinium-induced neurotoxicity.

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Amyloid precursor protein-mediated free radicals and oxidative damage: implications for the development and progression of Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Heme oxygenase-1 protects brain from acute excitotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Protective role of heme oxygenase-1 in oxidative stress-induced neuronal injury

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Oxidative stress hypothesis in Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Astaxanthin upregulates heme oxygenase-1 expression through ERK1/2 pathway and its protective effect against beta-amyloid-induced cytotoxicity in SH-SY5Y cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

based on heuristic

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A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Heme oxygenase-1: role in brain aging and neurodegeneration

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Regulatory mechanisms of cellular response to oxidative stress

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Neotrofin increases heme oxygenase-1 selectively in neurons

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Protective effects of heme oxygenase-1 against MPP(+)-induced cytotoxicity in PC-12 cells

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

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Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

based on heuristic

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Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

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https://pubmed.ncbi.nlm.nih.gov/22147269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12640-011-9292-5

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

release_hs32n4qk6fhsbcfmksi3fqxy7q

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https://api.fatcat.wiki/v0/release/hs32n4qk6fhsbcfmksi3fqxy7q

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22147269

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