Y654 of β-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization of β-catenin. (Q54546714)

31 May 2018

title

Y654 of β-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization of β-catenin. (English)

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31 May 2018

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Tomohiro Kajiguchi

1

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31 May 2018

Akira Katsumi

2

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31 May 2018

Ryohei Tanizaki

3

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31 May 2018

Hitoshi Kiyoi

4

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31 May 2018

Tomoki Naoe

5

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31 May 2018

publication date

4 January 2012

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31 May 2018

European Journal of Haematology

published in

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31 May 2018

volume

88

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31 May 2018

page(s)

314-320

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31 May 2018

issue

4

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31 May 2018

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

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Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

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FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates

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Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

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Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

21 January 2018

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Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

21 January 2018

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

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The role of FLT3 in haematopoietic malignancies

21 January 2018

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

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Regulation of beta-catenin structure and activity by tyrosine phosphorylation.

21 January 2018

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p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction

21 January 2018

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Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

21 January 2018

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Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target

21 January 2018

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FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells

21 January 2018

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KIT regulates tyrosine phosphorylation and nuclear localization of beta-catenin in mast cell leukemia

21 January 2018

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A novel FLT3 inhibitor FI-700 selectively suppresses the growth of leukemia cells with FLT3 mutations

21 January 2018

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Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

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Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

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Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

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Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.

21 January 2018

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Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential beta-catenin phosphorylation.

21 January 2018

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Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

21 January 2018

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Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor

21 January 2018

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Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

21 January 2018

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10.1111/J.1600-0609.2011.01738.X

21 January 2018

Identifiers

DOI

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31 May 2018

PubMed ID

22126602

1 reference

31 May 2018