Click chemistry for rapid labeling and ligation of RNA. (Q54628496)

1 June 2018

title

Click chemistry for rapid labeling and ligation of RNA. (English)

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1 June 2018

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Subha R Das

2

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author name string

Eduardo Paredes

series ordinal

1

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1 June 2018

publication date

1 January 2011

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1 June 2018

published in

ChemBioChem

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1 June 2018

volume

12

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1 June 2018

issue

1

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1 June 2018

page(s)

125-131

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1 June 2018

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

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CuI-Catalyzed Alkyne-Azide “Click” Cycloadditions from a Mechanistic and Synthetic Perspective

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Click chemistry and bioorthogonal reactions: unprecedented selectivity in the labeling of biological molecules.

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Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

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Click chemistry with DNA.

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In situ click chemistry: probing the binding landscapes of biological molecules

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Tricks with clicks: modification of peptidomimetic oligomers via copper-catalyzed azide-alkyne [3 + 2] cycloaddition

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Exploring RNA transcription and turnover in vivo by using click chemistry

21 January 2018

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New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes

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Reaction discovery enabled by DNA-templated synthesis and in vitro selection

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Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition

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Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching

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Conjugation of nucleosides and oligonucleotides by [3+2] cycloaddition

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Versatile 5'-functionalization of oligonucleotides on solid support: amines, azides, thiols, and thioethers via phosphorus chemistry.

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Synthesis of biotin-AMP conjugate for 5' biotin labeling of RNA through one-step in vitro transcription

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Synthesis of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its enzymatic incorporation at the 5'-termini of RNA molecules

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Efficient preparation of organic substrate-RNA conjugates via in vitro transcription.

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Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro

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Synthesis of guanosine 5'-conjugates and their use as initiator molecules for transcription priming

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3'-end labeling of RNA with recombinant yeast poly(A) polymerase.

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Joining of RNAs by splinted ligation

21 January 2018

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Optimizing splinted ligation of highly structured small RNAs.

21 January 2018

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Catalytic strategies of the hepatitis delta virus ribozymes

21 January 2018

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General acid catalysis by the hepatitis delta virus ribozyme

21 January 2018

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Crystal structure of a hepatitis delta virus ribozyme

21 January 2018

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Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA.

21 January 2018

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An important role of G638 in the cis-cleavage reaction of the Neurospora VS ribozyme revealed by a novel nucleotide analog incorporation method

21 January 2018

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Local conformational changes in the catalytic core of the trans-acting hepatitis delta virus ribozyme accompany catalysis

21 January 2018

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New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control

21 January 2018

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Crystal structure of a self-splicing group I intron with both exons

21 January 2018

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Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

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Combined Approaches to Site-Specific Modification of RNA

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Nucleotide analogues to investigate RNA structure and function

21 January 2018

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LC/MS analysis of cellular RNA reveals NAD-linked RNA

21 January 2018

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Lipid-conjugated oligonucleotides via "click chemistry" efficiently inhibit hepatitis C virus translation.

21 January 2018

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Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones

21 January 2018

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Cu-free click cycloaddition reactions in chemical biology

21 January 2018

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Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201000466

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1 June 2018

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1 June 2018