Caspase 8 is absent or low in many ex vivo gliomas. (Q54650436)

2 June 2018

title

Caspase 8 is absent or low in many ex vivo gliomas. (English)

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2 June 2018

author

Andrew H. Kaye

5

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2 June 2018

author name string

David M Ashley

1

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2 June 2018

Christopher D Riffkin

2

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2 June 2018

Andrea M Muscat

3

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2 June 2018

Melissa J Knight

4

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2 June 2018

Ulrike Novak

6

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2 June 2018

Christine J Hawkins

7

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2 June 2018

language of work or name

English

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publication date

1 October 2005

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2 June 2018

published in

Cancer

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2 June 2018

volume

104

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2 June 2018

issue

7

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2 June 2018

page(s)

1487-1496

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2 June 2018

Increased apoptosis in metastatic human colonic adenocarcinomas.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

DNA damage-induced apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Death receptor-induced cell killing

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Assignment of CASP8 to human chromosome band 2q33-->q34 and Casp8 to the murine syntenic region on chromosome 1B-proximal C by in situ hybridization

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Structure and chromosome localization of the human CASP8 gene

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Casper is a FADD- and caspase-related inducer of apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

I-FLICE, a Novel Inhibitor of Tumor Necrosis Factor Receptor-1- and CD-95-induced Apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

CASH, a novel caspase homologue with death effector domains

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Inhibition of fas death signals by FLIPs

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Activation of caspases-8 and -10 by FLIP(L).

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Phase I study of recombinant human tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

APO2 ligand: a novel lethal weapon against malignant glioma?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE)

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Interferon gamma is required for activation-induced death of T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Expression and methylation of CASP8 in neuroblastoma: identification of a promoter region

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Methylation analysis of formalin-fixed, paraffin-embedded sections using a nontoxic DNA extraction protocol

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Promoter methylation pattern of caspase-8, P16INK4A, MGMT, TIMP-3, and E-cadherin in medulloblastoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

DNA methylation of multiple promoter-associated CpG islands in meningiomas: relationship with the allelic status at 1p and 22q.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Aberrant CpG island methylation of multiple genes in ependymal tumors.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Aberrant gene promoter methylation in acute promyelocytic leukaemia: profile and prognostic significance

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Aberrant methylation of multiple genes in neuroblastic tumours. relationship with MYCN amplification and allelic status at 1p.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Interferon-gamma induces caspase-8 in neuroblastomas without affecting methylation of caspase-8 promoter

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

The flip side of FLIP

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Inactivating mutations of caspase-8 gene in colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Dominant expression of a novel splice variant of caspase-8 in human peripheral blood lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Alternative splicing of caspase-8 mRNA during differentiation of human leukocytes

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Mechanisms of resistance to TRAIL-induced apoptosis in cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.21323

7 January 2021

Identifiers

DOI

10.1002/CNCR.21323

1 reference

2 June 2018

1 reference

2 June 2018