Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet (Q54659066)

2 June 2018

title

Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet (English)

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https://api.crossref.org/works/10.1016/J.METABOL.2010.06.008

14 June 2024

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Hiroyuki Aburatani

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2 June 2018

author name string

Tomonori Muraoka

1

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2 June 2018

Kazutaka Aoki

2

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2 June 2018

Tomoyuki Iwasaki

3

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Kazuaki Shinoda

4

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Akinobu Nakamura

5

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Shuuichi Mori

7

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Kumpei Tokuyama

8

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Naoto Kubota

9

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Takashi Kadowaki

10

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Yasuo Terauchi

11

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language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20673929

14 June 2024

publication date

2 August 2010

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2 June 2018

full work available at URL

https://api.elsevier.com/content/article/PII:S0026049510001885?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/J.METABOL.2010.06.008

https://api.elsevier.com/content/article/PII:S0026049510001885?httpAccept=text/plain

14 June 2024

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https://api.crossref.org/works/10.1016/J.METABOL.2010.06.008

14 June 2024

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2 June 2018

volume

60

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issue

5

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2 June 2018

page(s)

617-628

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2 June 2018

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

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Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

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Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters.

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Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome

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Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice

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Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease

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Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice

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Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice

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Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

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Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice

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High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

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High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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Insulin resistance in the GK rat: decreased receptor number but normal kinase activity in liver

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Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

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SREBPs suppress IRS-2-mediated insulin signalling in the liver

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Identifiers

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2 June 2018

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2 June 2018