Citrus nobiletin ameliorates experimental colitis by reducing inflammation and restoring impaired intestinal barrier function. (Q55068125)

16 June 2018

title

Citrus nobiletin ameliorates experimental colitis by reducing inflammation and restoring impaired intestinal barrier function. (English)

1 reference

16 June 2018

0 references

1 reference

Yongjian Xiong

1

1 reference

16 June 2018

Dapeng Chen

2

1 reference

16 June 2018

Changchun Yu

3

1 reference

16 June 2018

Bochao Lv

4

1 reference

16 June 2018

Jinyong Peng

5

1 reference

16 June 2018

Jingyu Wang

6

1 reference

16 June 2018

Yuan Lin

7

1 reference

16 June 2018

publication date

16 March 2015

1 reference

16 June 2018

Molecular Nutrition and Food Research

published in

1 reference

16 June 2018

volume

59

1 reference

16 June 2018

issue

5

1 reference

16 June 2018

page(s)

829-842

1 reference

16 June 2018

Inflammatory bowel disease: cause and immunobiology

cites work

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Impact of a probiotic Enterococcus faecalis in a gnotobiotic mouse model of experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Genetics and pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Mechanism of IL-1β modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

TNF-α modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Intestinal mucosal barrier function in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Cellular and molecular mechanism of interleukin-1β modulation of Caco-2 intestinal epithelial tight junction barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: role of cytoskeletal involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Akt is a downstream target of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Oral administration of the flavonoid myricitrin prevents dextran sulfate sodium-induced experimental colitis in mice through modulation of PI3K/Akt signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Development of high-energy amorphous solid dispersion of nanosized nobiletin, a citrus polymethoxylated flavone, with improved oral bioavailability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Nobiletin, a polymethoxylated flavonoid from citrus, shows anti-angiogenic activity in a zebrafish in vivo model and HUVEC in vitro model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Permeability determination and pharmacokinetic study of nobiletin in rat plasma and brain by validated high-performance liquid chromatography method

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Anti-neuroinflammatory activity of nobiletin on suppression of microglial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Hymenaea stigonocarpa Mart. ex Hayne: A tropical medicinal plant with intestinal anti-inflammatory activity in TNBS model of intestinal inflammation in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Early weaning stress impairs development of mucosal barrier function in the porcine intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

IL-1beta causes an increase in intestinal epithelial tight junction permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Ontogenesis of myosin light chain kinase mRNA and protein content in guinea pig tracheal smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Regulation of the inflammatory response: enhancing neutrophil infiltration under chronic inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Macrophage pro-inflammatory cytokine secretion is enhanced following interaction with autologous platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Ropivacaine attenuates endotoxin plus hyperinflation-mediated acute lung injury via inhibition of early-onset Src-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Intestinal barrier dysfunction in inflammatory bowel diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Glutamine supplementation prevents exercise-induced neutrophil apoptosis and reduces p38 MAPK and JNK phosphorylation and p53 and caspase 3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Combined arginine and glutamine decrease release of de novo synthesized leukotrienes and expression of proinflammatory cytokines in activated human intestinal mast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-alpha-induced regulation of myosin light chain kinase gene activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Non-proteolytic house dust mite allergen, Der p 2, upregulated expression of tight junction molecule claudin-2 associated with Akt/GSK-3β/β-catenin signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

TNFalpha-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFkappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3K/Akt/NF-κB pathway in human non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Modeling of intestinal drug absorption: roles of transporters and metabolic enzymes (for the Gillette Review Series).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Comparison between permeability coefficients in rat and human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201400614

21 January 2018

Identifiers

DOI

10.1002/MNFR.201400614

1 reference

16 June 2018

1 reference

16 June 2018