Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations. (Q55068987)

From Wikidata

Jump to navigation Jump to search

scientific article published on 24 December 2014

Language	Label	Description	Also known as
English	Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.	scientific article published on 24 December 2014

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272608

Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations. (English)

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272608

virtual screening

1 reference

based on heuristic

inferred from title

Federica Moraca

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Simona Distinto

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Francesco Ortuso

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Elias Maccioni

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Anna Artese

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lucia Parrotta

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

0 references

publication date

24 December 2014

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272608

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

206-223

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

copyright license

Creative Commons Attribution 4.0 International

24 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Detection of quadruplex DNA structures in human telomeres by a fluorescent carbazole derivative

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

The major G-quadruplex formed in the human platelet-derived growth factor receptor β promoter adopts a novel broken-strand structure in K+ solution

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Bioinformatics approaches to quadruplex sequence location

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

G-quadruplexes in promoters throughout the human genome

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Hunting G-quadruplexes

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Highly prevalent putative quadruplex sequence motifs in human DNA

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Gene function correlates with potential for G4 DNA formation in the human genome

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Quantitative visualization of DNA G-quadruplex structures in human cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Electrospray ionization mass spectrometric exploration of the high-affinity binding of three natural alkaloids with the mRNA G-quadruplex in the BCL2 5'-untranslated region

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Quadruplex DNA: sequence, topology and structure

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

G-quadruplexes: targets in anticancer drug design.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

G-quadruplex DNA structures--variations on a theme

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Inhibition of telomerase by G-quartet DNA structures

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

DNA and its associated processes as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Telomere maintenance as a target for anticancer drug discovery

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

G-quadruplex interacting agents targeting the telomeric G-overhang are more than simple telomerase inhibitors

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Telomere maintenance mechanisms as a target for drug development

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Novel anticancer therapeutics targeting telomerase

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Function of the c-Myc oncogenic transcription factor.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

The c-MYC NHE III(1): function and regulation

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Activating transcription from single stranded DNA.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

DNA tetraplex formation in the control region of c-myc

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structure of the biologically relevant G-quadruplex in the c-MYC promoter

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structure-based discovery of natural-product-like TNF-α inhibitors

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

A natural product-like inhibitor of NEDD8-activating enzyme

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Drug repositioning by structure-based virtual screening

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Discovery of a natural product-like c-myc G-quadruplex DNA groove-binder by molecular docking

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Natural products as sources of new drugs over the 30 years from 1981 to 2010

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Sanguinarine interacts with chromatin, modulates epigenetic modifications, and transcription in the context of chromatin

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Natural and synthetic G-quadruplex interactive berberine derivatives.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: A new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structural insights into G-quadruplexes: towards new anticancer drugs

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Identification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

A spectroscopic investigation of the interaction between c-MYC DNA and tetrapyridinoporphyrazinatozinc(II).

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Scalable molecular dynamics with NAMD

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Lead- and drug-like compounds: the rule-of-five revolution

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Automatic atom type and bond type perception in molecular mechanical calculations

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Targeting telomeres and telomerase

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

Spectroscopic, Molecular Modeling, and NMR-Spectroscopic Investigation of the Binding Mode of the Natural Alkaloids Berberine and Sanguinarine to Human Telomeric G-Quadruplex DNA

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20010206

21 January 2018

FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetraplex DNA specific ligands based on the fluorenone-carboxamide scaffold

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of DNA topoisomerase I by natural and synthetic mono- and dimeric protoberberine alkaloids

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity of an indolyl berberine derivative for tetrameric G-quadruplex DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of berberine, palmatine, coralyne, and sanguinarine to quadruplex DNA: A comparative spectroscopic and calorimetric study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation and recognition of G-quadruplex in promoter of c-myb oncogene by electrospray ionization mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of the G-quadruplex conformation in the development of novel therapeutic and diagnostic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of non-covalent interaction of natural flexible cyclic molecules with telomeric RNA G-quadruplexes by electrospray ionization mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of recognition of quadruplexes human telomere and c-myc promoter by the putative anticancer agent sanguinarine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrospray ionization mass spectrometry probing of binding affinity of berbamine, a flexible cyclic alkaloid from traditional Chinese medicine, with G-quadruplex DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25547724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES20010206

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25547724%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q55068987&oldid=1858957158"