Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis (Q55106522)

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25 March 2020

title

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis (English)

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25 March 2020

John H. Adams

16

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Min Zhang

1

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Jenna Oberstaller

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Swamy Rakesh Adapa

6

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Deborah Casandra

9

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Julian Rayner

14

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Rays H Y Jiang

15

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author name string

Chengqi Wang

2

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Xiangyun Liao

5

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Kenneth Udenze

7

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Matthew Mayho

10

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Jacqueline Brown

11

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Suzanne Li

12

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Justin Swanson

13

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Iraad F Bronner

8

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language of work or name

English

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publication date

1 May 2018

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volume

360

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page(s)

eaap7847

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issue

6388

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Transposon mutagenesis of baculoviruses: analysis of Trichoplusia ni transposon IFP2 insertions within the FP-locus of nuclear polyhedrosis viruses

25 March 2020

cites work

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12 December 2020

Transposon-mediated mutagenesis of a baculovirus.

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12 December 2020

Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes

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12 December 2020

Genome sequence of the human malaria parasite Plasmodium falciparum

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12 December 2020

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

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12 December 2020

Targeted disruption of maebl in Plasmodium falciparum.

1 reference

12 December 2020

A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes

1 reference

12 December 2020

Acquisition of Host Cell DNA Sequences by Baculoviruses: Relationship Between Host DNA Insertions and FP Mutants of Autographa californica and Galleria mellonella Nuclear Polyhedrosis Viruses

1 reference

12 December 2020

piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome

1 reference

12 December 2020

Nucleosome landscape and control of transcription in the human malaria parasite

1 reference

12 December 2020

New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq

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12 December 2020

Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite

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12 December 2020

Jumbled genomes: missing Apicomplexan synteny

1 reference

12 December 2020

CCR4-associated factor 1 coordinates the expression of Plasmodium falciparum egress and invasion proteins

1 reference

12 December 2020

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

1 reference

12 December 2020

EuPathDB: the eukaryotic pathogen database

1 reference

12 December 2020

Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis

1 reference

12 December 2020

Atypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparum

1 reference

12 December 2020

Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission

1 reference

12 December 2020

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.

1 reference

12 December 2020

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

1 reference

12 December 2020

Spread of artemisinin resistance in Plasmodium falciparum malaria

1 reference

12 December 2020

Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum.

1 reference

12 December 2020

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

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12 December 2020

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

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12 December 2020

Advances in molecular genetic systems in malaria

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12 December 2020

Identification and characterization of essential genes in the human genome.

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12 December 2020

Gene essentiality and synthetic lethality in haploid human cells

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12 December 2020

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery.

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12 December 2020

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

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12 December 2020

Structure- and function-based design of Plasmodium-selective proteasome inhibitors

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12 December 2020

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants

1 reference

12 December 2020

Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way

1 reference

12 December 2020

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

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12 December 2020

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

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12 December 2020

The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread

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12 December 2020

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

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12 December 2020

Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

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12 December 2020

Identifiers

DOI

10.1126/SCIENCE.AAP7847

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29724925%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

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25 March 2020

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