Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches. (Q55118845)

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English	Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches.	scientific article

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scholarly article

1 reference

Europe PubMed Central

21 June 2018

http://europepmc.org/abstract/PMC/5993118

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches. (English)

1 reference

Europe PubMed Central

21 June 2018

http://europepmc.org/abstract/PMC/5993118

Streptomyces lividans

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Streptomyces argillaceus

1 reference

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3,3'-Dihydroxyisorenieratene

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4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-(4-methoxy-2,3,6-trimethylphenyl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-2,3,5-trimethylphenol

1 reference

1 reference

beta-Isorenieratene

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1 reference

1-methoxy-2,3,5-trimethyl-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,3,6-trimethylphenyl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]benzene

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1 reference

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Dimethoxyisorenieralene

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3-hydroxyisorenieratene

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1 reference

1 reference

1 reference

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[8-Butyl-3-[(3-formamido-2-hydroxybenzoyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylbutanoate

1 reference

Streptomyces anthocyanicus

1 reference

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29795673%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Margarita Díaz

5

1 reference

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31 May 2020

Ramón I Santamaría

6

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31 May 2020

author name string

Adriana Becerril

1

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31 May 2020

Susana Álvarez

2

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31 May 2020

Alfredo F Braña

3

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31 May 2020

Sergio Rico

4

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31 May 2020

José A Salas

7

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31 May 2020

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publication date

24 May 2018

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21 June 2018

http://europepmc.org/abstract/PMC/5993118

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31 May 2020

13

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31 May 2020

e0198145

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31 May 2020

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31 May 2020

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Creative Commons Attribution 4.0 International

24 May 2018

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19 March 2024

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access restriction status

1 reference

based on heuristic

inferred from online access status

CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine Alkaloids Argimycins P.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Combined LC/UV/MS and NMR Strategies for the Dereplication of Marine Natural Products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Taxonomy, Physiology, and Natural Products of Actinobacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic Window

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Minimum Information about a Biosynthetic Gene cluster.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Production of specialized metabolites by Streptomyces coelicolor A3(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Deciphering the regulon of Streptomyces coelicolor AbrC3, a positive response regulator of antibiotic production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Thoughts and facts about antibiotics: where we are now and where we are heading

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22 June 2018

Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Biosynthesis of the RNA polymerase inhibitor streptolydigin in Streptomyces lydicus: tailoring modification of 3-methyl-aspartate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Genomic basis for natural product biosynthetic diversity in the actinomycetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tü4055: cluster analysis and assignment of functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Big effects from small changes: possible ways to explore nature's chemical diversity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

22 June 2018

New Insights into the Biosynthesis Pathway of Polyketide Alkaloid Argimycins P in Streptomyces argillaceus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

Secondary Metabolites Produced during the Germination of Streptomyces coelicolor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

A phylogenetic and evolutionary analysis of antimycin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

Activation and mechanism of a cryptic oviedomycin gene cluster via the disruption of a global regulatory gene, adpA, in Streptomyces ansochromogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

Genome rearrangements of Streptomyces albus J1074 lead to the carotenoid gene cluster activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

3,3'-Dihydroxyisorenieratene and isorenieratene prevent UV-induced DNA damage in human skin fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

A sigmaB-like factor responsible for carotenoid biosynthesis in Streptomyces griseus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5993118

13 August 2018

New carotenoids fromStreptomyces mediolani n. sp

1 reference

https://pubmed.ncbi.nlm.nih.gov/29795673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of genes from Streptomyces griseus involved in the synthesis of isorenieratene, a carotenoid with aromatic end groups, revealed a novel type of carotenoid desaturase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29795673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic control for light-induced carotenoid production in non-phototrophic bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/29795673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

1 reference

https://pubmed.ncbi.nlm.nih.gov/29795673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phylogenetic and evolutionary analysis of antimycin biosynthesis

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.1371/JOURNAL.PONE.0198145

Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

2 references

12 April 2024

https://opencitations.net/index/api/v1/references/10.1371/JOURNAL.PONE.0198145

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.180.18.4929-4937.1998

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10.1371/JOURNAL.PONE.0198145

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Europe PubMed Central

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31 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29795673%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29795673%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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