NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. (Q55469625)

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28 December 2019

title

NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition (English)

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28 December 2019

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Klaus-Michael Debatin

6

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28 December 2019

Simone Fulda

7

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28 December 2019

Mike-Andrew Westhoff

2

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28 December 2019

Ralf Michael Zwacka

5

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28 December 2019

author name string

K La Ferla-Brühl

1

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28 December 2019

S Karl

3

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28 December 2019

H Kasperczyk

4

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28 December 2019

language of work or name

English

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publication date

7 August 2006

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28 December 2019

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28 December 2019

volume

26

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28 December 2019

issue

4

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28 December 2019

page(s)

571-582

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

28 December 2019

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Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells

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NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells

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Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

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Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity

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Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IkappaBbeta

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The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells

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NF-kappaB in cancer: from innocent bystander to major culprit

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The IKK NF-kappa B system: a treasure trove for drug development

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Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy

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7 January 2021

Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors.

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7 January 2021

Ubiquitin-proteasome pathway as a primary defender against TRAIL-mediated cell death

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Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells

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Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

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7 January 2021

Aberrant nuclear factor-kappaB activity and its participation in the growth of human malignant astrocytoma

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7 January 2021

Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

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7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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7 January 2021

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

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7 January 2021

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Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas

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Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas

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Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

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NF-kappaB kinetics predetermine TNF-alpha sensitivity of colorectal cancer cells

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209841

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16909119%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 December 2019

1018845904

0 references

1 reference