Leptin: a review of its peripheral actions and interactions (Q56169405)

Europe PubMed Central

title

Leptin: a review of its peripheral actions and interactions (English)

0 references

author name string

S Margetic

1

0 references

C Gazzola

2

0 references

GG Pegg

3

0 references

RA Hill

International Journal of Obesity

4

0 references

language of work or name

English

0 references

publication date

November 2002

0 references

published in

0 references

volume

26

0 references

page(s)

1407-1433

0 references

issue

11

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/sj.ijo.0802142

0 references

cites work

The Nutrition Society Medical Lecture. Obesity: from molecules to man.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Worldwide epidemiology of obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

What is a healthy weight for middle aged women?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Weight-reducing effects of the plasma protein encoded by the obese gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Effects of the obese gene product on body weight regulation in ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Abnormal splicing of the leptin receptor in diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The stomach is a source of leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A nutrient-sensing pathway regulates leptin gene expression in muscle and fat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin and the regulation of body weight

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Modulation of obese gene expression in rat brown and white adipose tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Immunohistochemical detection of the ob gene product (leptin) in rat white and brown adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Short photoperiod reduces leptin gene expression in white and brown adipose tissue of Djungarian hamsters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Effects of beta-adrenoceptor subtype stimulation on obese gene messenger ribonucleic acid and on leptin secretion in mouse brown adipocytes differentiated in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin gene is expressed in rat brown adipose tissue at birth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Direct effects of leptin on brown and white adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Quantification of the full length leptin receptor (OB-Rb) in human brown and white adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of the beta3-adrenoceptor in the control of leptin expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Difference in leptin mRNA levels between omental and subcutaneous abdominal adipose tissue from obese humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin secretion from subcutaneous and visceral adipose tissue in women.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

In vivo and in vitro ob gene expression and leptin secretion in rat adipocytes: evidence for a regional specific regulation by sex steroid hormones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Placental leptin: an important new growth factor in intrauterine and neonatal development?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Cyclical variations in the abundance of leptin receptors, but not in circulating leptin, correlate with NPY expression during the oestrous cycle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Synthesis of leptin in human placenta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor in human term placenta: in situ hybridization and immunohistochemical localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin and reproduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Presence of leptin receptors in rat small intestine and leptin effect on sugar absorption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin gene expression in the brain and pituitary gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin and leptin receptor expression in rat and mouse pituitary cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin expression in human mammary epithelial cells and breast milk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Splice variants of the OB receptor gene are differentially expressed in brain and peripheral tissues of mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Cloning the chicken leptin gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Prolonged exercise decreases serum leptin concentrations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hypoleptinemia in female and male elite gymnasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The effect of exercise on ob gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute and chronic effects of exercise on leptin levels in humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin: physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Circulating leptin levels are modulated by fasting, cold exposure and insulin administration in lean but not Zucker (fa/fa) rats as measured by ELISA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Cold exposure inhibits leptin secretion in vitro by a direct and non-specific action on adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the beta 3-adrenoceptor agonists BRL 35135A and ZD2079.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regulation of leptin production in cultured mature white adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Physiological response to acute endotoxemia in swine: effect of genotype on energy metabolites and leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Effects of fasting and refeeding on the level of uncoupling protein mRNA in rat brown adipose tissue: evidence for diet-induced and cold-induced responses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Fasting and leptin modulate adipose and muscle uncoupling protein: divergent effects between messenger ribonucleic acid and protein expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Plasma leptin in depressed patients and healthy controls.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Relationship of serum leptin levels and selected nutritional parameters in patients with protein-caloric malnutrition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Activation of beta(3) adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Demonstration of an in vivo functional beta 3-adrenoceptor in man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin: fundamental aspects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of leptin in fat regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Receptor-mediated regional sympathetic nerve activation by leptin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

1 reference

7 January 2021

Defective STAT signaling by the leptin receptor in diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The relationship of tissue localization, distribution and turnover to feeding after intraperitoneal 125I-leptin administration to ob/ob and db/db mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Localization of leptin receptor splice variants in mouse peripheral tissues by immunohistochemistry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptors expressed on pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The role of neuropeptide Y in the antiobesity action of the obese gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Cytokine receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Localization of leptin binding domain in the leptin receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor of Zucker fatty rat performs reduced signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Divergent signaling capacities of the long and short isoforms of the leptin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin and its receptors: regulators of whole-body energy homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Mitogenic signaling and inhibition of apoptosis via the erythropoietin receptor Box-1 domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Distribution of the transcription factor signal transducer and activator of transcription 3 in the rat central nervous system and dorsal root ganglia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The role of SOCS-3 in leptin signaling and leptin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin enters the brain by a saturable system independent of insulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A short form of leptin receptor performs signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A novel leptin receptor isoform in rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin directly stimulates catecholamine secretion and synthesis in cultured porcine adrenal medullary chromaffin cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Characterization and localization of leptin receptors in the rat kidney.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regional localization of specific [125I]leptin binding sites in rat forebrain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor action in hepatic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Identification of targets of leptin action in rat hypothalamus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of leptin receptor in lung: leptin as a growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Binding of a pure 125I-monoiodoleptin analog to mouse tissues: a developmental study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin: its pharmacokinetics and tissue distribution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Influence of insulin antibodies on pharmacokinetics and bioavailability of recombinant human and highly purified beef insulins in insulin dependent diabetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Actions of an IGF-I-enhancing antibody on IGF-I pharmacokinetics and tissue distribution: increased IGF-I bioavailability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I) and an analogue LR3IGF-I in pregnant rats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Adipose tissue leptin production and plasma leptin kinetics in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Pharmacokinetics of human leptin in mice and rhesus monkeys

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Evidence for leptin binding to proteins in serum of rodents and humans: modulation with obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A role for leptin in hemopoieses?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin promotes aggregation of human platelets via the long form of its receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Biological action of leptin as an angiogenic factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin, the product of Ob gene, promotes angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: potential role in intimal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Up-regulation of blood-brain barrier short-form leptin receptor gene products in rats fed a high fat diet

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Early onset of reproductive function in normal female mice treated with leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

1 reference

7 January 2021

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Circulating leptin levels during ovulation induction: relation to adiposity and ovarian morphology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin treatment rescues the sterility of genetically obese ob/ob males

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Estrogen increases in vivo leptin production in rats and human subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Insulin and cortisol promote leptin production in cultured human fat cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

1 reference

7 January 2021

Leptin in human reproduction: serum leptin levels in pregnant and lactating women

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin levels in pregnant women and newborn infants: gender differences and reduction during the neonatal period.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Concentrations of leptin in the serum of pregnant, lactating, and cycling rats and of leptin messenger ribonucleic acid in rat placental tissue.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Serum leptin levels do not rise during pregnancy in age-matched rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The brain-pituitary-adipocyte axis: role of leptin in modulating neuroendocrine function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Current concepts concerning the role of leptin in reproductive function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Elevated leptin concentrations in pregnancy and lactation: possible role as a modulator of substrate utilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Relationship between concentration of serum leptin and fetal growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of leptin in hypothalamic-pituitary function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin accelerates the onset of puberty in normal female mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin is a metabolic gate for the onset of puberty in the female rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Circulating leptin does not appear to provide a signal for triggering the initiation of puberty in the male rhesus monkey (Macaca mulatta)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

A longitudinal study of leptin during development in the male rhesus monkey: the effect of body composition and season on circulating leptin levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin's actions on the reproductive axis: perspectives and mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Physiological insulinemia acutely modulates plasma leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Supraphysiological hyperinsulinemia increases plasma leptin concentrations after 4 h in normal subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Transient increase in obese gene expression after food intake or insulin administration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Relation of free and specifically bound leptin to insulin secretion in patients with impaired glucose tolerance (IGT).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Responses of leptin to short-term fasting and refeeding in humans: a link with ketogenesis but not ketones themselves

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Increased OB gene expression leads to elevated plasma leptin concentrations in patients with chronic primary hyperinsulinemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Serum leptin and insulin concentrations in patients with insulinoma before and after surgery.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Insulin induces rapid changes of plasma leptin in lean but not in genetically obese (fa/fa) rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Plasma leptin and insulin relationships in obese and nonobese humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin: a potent inhibitor of insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Direct stimulation of basal insulin secretion by physiological concentrations of leptin in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Failure of human and mouse leptin to affect insulin, glucagon and somatostatin secretion by the perfused rat pancreas at physiological glucose concentration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Do leptin receptors play a functional role in the endocrine pancreas?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Peripheral metabolic actions of leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin inhibits insulin binding in isolated rat adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin impairs metabolic actions of insulin in isolated rat adipocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Association of poorly controlled diabetes with low serum leptin in morbid obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Circulating insulin concentrations, smoking, and alcohol intake are important independent predictors of leptin in young healthy men.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Effects of nutritional status and aging on leptin gene expression in mice: importance of glucose

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute stimulation of glucose metabolism in mice by leptin treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Modulation of insulin activities by leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin Directly Alters Lipid Partitioning in Skeletal Muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin inhibits glycogen synthesis in the isolated soleus muscle of obese (ob/ob) mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Acute leptin action on insulin blood level and liver insulin receptor in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hexosamines as mediators of nutrient sensing and regulation in diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of the glucosamine pathway in fat-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Glucosamine regulation of glucose metabolism in cultured human skeletal muscle cells: divergent effects on glucose transport/phosphorylation and glycogen synthase in non-diabetic and type 2 diabetic subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Insulin induces the translocation of the fatty acid transporter FAT/CD36 to the plasma membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin has acute effects on glucose and lipid metabolism in both lean and gold thioglucose-obese mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Adrenal steroid receptors: interactions with brain neuropeptide systems in relation to nutrient intake and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Glucocorticoids reverse leptin effects on food intake and body fat in mice without increasing NPY mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

High leptin concentrations in serum of very obese children are further stimulated by dexamethasone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Weight regulation, leptin and growth hormone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Relationship between serum leptin and the insulin-like growth factor-I system in humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin is a potent stimulator of spontaneous pulsatile growth hormone (GH) secretion and the GH response to GH-releasing hormone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

The in vitro effect of leptin on basal and growth hormone-releasing hormone-stimulated growth hormone secretion from the ovine pituitary gland.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin receptor and neuropeptide Y gene expression in the sheep brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Recombinant porcine leptin reduces feed intake and stimulates growth hormone secretion in swine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Growth hormone regulates leptin gene expression in bovine adipose tissue: correlation with adipose IGF-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Growth hormone directly inhibits leptin gene expression in visceral fat tissue in fatty Zucker rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hormonal regulation of leptin mRNA expression and preadipocyte recruitment and differentiation in porcine primary cultures of S-V cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Contribution of androgens to the gender difference in leptin production in obese children and adolescents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Reduced ob mRNA in hypophysectomised rats is not restored by growth hormone (GH), but further suppressed by exogenously administered insulin-like growth factor (IGF) I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin is suppressed during infusion of recombinant human insulin-like growth factor I (rhIGF I) in normal rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Tumor necrosis factor increases serum leptin levels in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Interleukins and tumor necrosis factor as inhibitors of food intake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin: in search of role(s) in human physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Downregulation of leptin by free fatty acids in rat adipocytes: effects of triacsin C, palmitate, and 2-bromopalmitate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of leptin and beta 3-adrenergic receptors in rat adipose tissue in altered thyroid states

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Regulation of expression of leptin mRNA and secretion of leptin by thyroid hormone in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Role of thyroid hormones on serum leptin levels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Hyperleptinemia in chronic renal failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Expression of ob gene in adipose cells. Regulation by insulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Dexamethasone increases leptin expression in humans in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Tumour necrosis factor-alpha exerts dual effects on human adipose leptin synthesis and release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin mRNA expression and serum leptin concentrations as influenced by age, weight, and estradiol in pigs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Treatment with CL 316,243, a beta 3-adrenoceptor agonist, reduces serum leptin in rats with diet- or aging-associated obesity, but not in Zucker rats with genetic (fa/fa) obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Is leptin sensitivity the link between smoking cessation and weight gain?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Serum leptin levels in Mexican Americans and non-Hispanic whites: association with body mass index and cigarette smoking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Is leptin involved in the acute anorectic effect of nicotine?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin inhibits insulin secretion and reduces insulin mRNA levels in rat isolated pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Leptin suppresses basal insulin secretion from rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021

Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802142

7 January 2021