DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery (Q56432854)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200034%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200034%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Carlos Garcia-Estrada

1

1 reference

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Christopher Fernandez-Prada

19 January 2020

3

1 reference

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Francisco A. Rojo Vazquez

19 January 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200034%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Rafael Balaña-Fouce

5

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19 January 2020

author name string

Christopher Fernández Prada

2

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19 January 2020

language of work or name

English

0 references

publication date

3 March 2010

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19 January 2020

number of pages

11

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Proceedings of the Royal Society B

inferred from page(s)

published in

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19 January 2020

volume

277

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19 January 2020

issue

1689

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19 January 2020

page(s)

1777-1787

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Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins

19 January 2020

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An unusual type IB topoisomerase from African trypanosomes

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Characterization of a Leishmania donovani gene encoding a protein that closely resembles a type IB topoisomerase

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Topoisomerases in kinetoplastids

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Molecular cloning of apicoplast-targeted Plasmodium falciparum DNA gyrase genes: unique intrinsic ATPase activity and ATP-independent dimerization of PfGyrB subunit

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A plastid organelle as a drug target in apicomplexan parasites.

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Targeting the transcriptional and translational machinery of the endosymbiotic organelle in apicomplexans

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Pyronaridine: A new antimalarial drug

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The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

21 January 2018

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Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii

21 January 2018

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Adverse drug reactions to treatments for ocular toxoplasmosis: a retrospective chart review.

21 January 2018

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Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage

21 January 2018

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21 January 2018

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Cryptosporidiosis and the challenges of chemotherapy

21 January 2018

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Features of apoptosis in Plasmodium falciparum erythrocytic stage through a putative role of PfMCA1 metacaspase-like protein.

21 January 2018

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Spread and evolution of Plasmodium falciparum drug resistance

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A novel nuclear localization signal in human DNA topoisomerase I

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Evolution of the Apicomplexa: where are we now?

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The structure of supercoiled intermediates in DNA replication

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21 January 2018

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A novel active DNA topoisomerase I in Leishmania donovani.

21 January 2018

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21 January 2018

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Cellular roles of dna topoisomerases: a molecular perspective

21 January 2018

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Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase.

21 January 2018

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21 January 2018

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The role of histidine 632 in catalysis by human topoisomerase I.

21 January 2018

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21 January 2018

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21 January 2018

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Functional expression of a DNA-topoisomerase IB from Cryptosporidium parvum

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Energy coupling in type II topoisomerases: why do they hydrolyze ATP?

29 September 2018

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Origin and evolution of DNA topoisomerases

29 September 2018

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Mitochondrial topoisomerases and alternative splicing of the human TOP1mt gene

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Repair of and checkpoint response to topoisomerase I-mediated DNA damage

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Partial purification of mitochondrial DNA topoisomerase II from Plasmodium falciparum and its sensitivity to inhibitors

29 September 2018

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29 September 2018

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Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA

29 September 2018

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Efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal models

29 September 2018

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29 September 2018

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Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro

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29 September 2018

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Purification and characterization of human topoisomerase I mutants

29 September 2018

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Conformational and thermodynamic properties of supercoiled DNA.

29 September 2018

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Identification of a type II topoisomerase gene from Cryptosporidium parvum.

29 September 2018

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Structure of chromatin. I: Levels of DNA organization in the nucleus; nucleosome and chromatin fibres

29 September 2018

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The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum

29 September 2018

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Purification and characterization of Plasmodium berghei DNA topoisomerases I and II: drug action, inhibition of decatenation and relaxation, and stimulation of DNA cleavage.

29 September 2018

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DNA topoisomerase II inhibitors

29 September 2018

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12 December 2020

Communication between the ATPase and cleavage/religation domains of human topoisomerase IIalpha

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Partial purification and characterization of DNA topoisomerase II from Plasmodium falciparum

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Efficacy of azithromycin for treating Babesia microti infection in the hamster model

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12 December 2020

Purification of a DNA topoisomerase II from the hyperthermophilic archaeon Sulfolobus shibatae. A thermostable enzyme with both bacterial and eucaryal features

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12 December 2020

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

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Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer

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Topoisomerase II inhibitors induce cleavage of nuclear and 35-kb plastid DNAs in the malarial parasite Plasmodium falciparum

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12 December 2020

Identifiers

DOI

10.1098/RSPB.2009.2176

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200034%20AND%20SRC:MED&resulttype=core&format=json

release_vampbe3cwjbj5limdl7rea73rm

19 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/vampbe3cwjbj5limdl7rea73rm

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200034%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference