Emerging and potential therapies for Alzheimer's disease (Q56449371)

Expert Opinion on Therapeutic Targets

Europe PubMed Central

title

Emerging and potential therapies for Alzheimer's disease (English)

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Nigel M Hooper

3

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author name string

Heledd H Griffiths

series ordinal

1

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Isobel J Morten

series ordinal

2

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language of work or name

English

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publication date

15 May 2008

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published in

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volume

12

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issue

6

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page(s)

693-704

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cites work

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The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

21 January 2018

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Copper reduction by the octapeptide repeat region of prion protein: pH dependence and implications in cellular copper uptake

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Reactive oxygen species-mediated beta-cleavage of the prion protein in the cellular response to oxidative stress

21 January 2018

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Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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Membrane topology influences N-glycosylation of the prion protein

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Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

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Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases

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An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

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Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease

21 January 2018

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The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation

21 January 2018

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Heparin promotes beta-secretase cleavage of the Alzheimer's amyloid precursor protein

21 January 2018

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Identification of the heparan sulfate binding sites in the cellular prion protein

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A systematic review of prion therapeutics in experimental models

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