Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family (Q56592584)

Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1

Europe PubMed Central

title

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family (English)

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author name string

B. Hagenbuch

series ordinal

1

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C. Gui

series ordinal

2

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language of work or name

English

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publication date

August 2008

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published in

Xenobiotica

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volume

38

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issue

7-8

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page(s)

778-801

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cites work

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Structure and mechanism of the lactose permease of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular characterization of human and rat organic anion transporter OATP-D

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

P-glycoprotein: from genomics to mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

On the statistical assessment of classifiers using DNA microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Multispecific amphipathic substrate transport by an organic anion transporter of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular cloning and functional characterization of the bovine (Bos taurus) organic anion transporting polypeptide Oatp1a2 (Slco1a2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Intestinal drug transporter expression and the impact of grapefruit juice in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Modification of OATP2B1-mediated transport by steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Cellular entry of thyroid hormones by organic anion transporting polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

The superfamily of organic anion transporting polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Expression cloning of a rat liver Na(+)-independent organic anion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Drug binding domains of MRP1 (ABCC1) as revealed by photoaffinity labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Pharmacogenomics of human OATP transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Human hepatobiliary transport of organic anions analyzed by quadruple-transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

N-glycosylation controls functional activity of Oatp1, an organic anion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular characterization and inhibition of amanitin uptake into human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

The effects of ergoloid mesylates and ginkgo biloba on the pharmacokinetics of ticlopidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of influx transporter for the quinolone antibacterial agent levofloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of phalloidin uptake systems of rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Organic anion transporting polypeptides of the OATP/SLCO superfamily: identification of new members in nonmammalian species, comparative modeling and a potential transport mode.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Human liver-specific organic anion transporter-2 is a potent prognostic factor for human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Possible involvement of organic anion transporting polypeptide 1c1 in the photoperiodic response of gonads in birds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells: involvement of organic anion transporting polypeptide (OATP)-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Involvement of estrone-3-sulfate transporters in proliferation of hormone-dependent breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Suppression of cell proliferation by inhibition of estrone-3-sulfate transporter in estrogen-dependent breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular mechanisms for the hepatic uptake of magnetic resonance imaging contrast agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of steroid sulfate transport processes in the human mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Hepatic uptake of the novel antifungal agent caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular mechanisms of prostaglandin transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

21 January 2018

Prostaglandin transport

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Identification and characterization of novel rat and human gonad-specific organic anion transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Characterization of hepatobiliary transport systems of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

Structure of the multidrug transporter EmrD from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951

A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250801986951