CTLA-4 blockade in murine bone marrow chimeras induces a host-derived antileukemic effect without graft-versus-host disease (Q56901286)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

CTLA-4 blockade in murine bone marrow chimeras induces a host-derived antileukemic effect without graft-versus-host disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Peter Vandenberghe

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Fevery S

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Billiau AD

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Rutgeerts O

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Lenaerts C

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Goebels J

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Landuyt W

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Kasran A

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Boon L

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Sagaert X

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

De Wolf-Peeters C

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Waer M

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

17 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

1451-1459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

Molecules and mechanisms of the graft-versus-leukaemia effect

30 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cancer immunotherapy: breaking the barriers to harvest the crop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

CTLA-4: a negative regulator of autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Maximizing optimal hematopoietic stem cell donor selection from registries of unrelated adult volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Transplantation tolerance and autoimmunity after xenogeneic thymus transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Type 2 autoimmune hepatitis murine model: the influence of genetic background in disease development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Diagnosis and treatment of autoimmune hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Graft-versus-host disease and graft-versus-leukemia after donor leukocyte infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Host MHC class II+ antigen-presenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Mechanisms of the antitumor responses and host-versus-graft reactions induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: a critical role for recipient CD4+ T cells and recipient leukocyte infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Thymocyte development is normal in CTLA-4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Regulatory T cells in transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Regulatory T cells in immunologic self-tolerance and autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

CD4+CD25+ regulatory T cells and graft-versus-host disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Regulatory T cells in immune surveillance and treatment of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can regulate dendritic cell-induced activation and cytotoxicity of CD8(+) T cells independently of CD4(+) T cell help.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

Antileukemic Effect of Graft-versus-Host Disease in Human Recipients of Allogeneic-Marrow Grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone marrow transplants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Graft-versus-leukemia effect in minor antigen mismatched chimeras given delayed donor leucocyte infusion: immunoregulatory aspects and role of donor T and ASGM1-positive cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Graft-versus-host reactivity and graft-versus-leukemia effect in murine allogeneic bone marrow chimeras conditioned with total body irradiation or total lymphoid irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

NOD bone marrow-derived dendritic cells are modulated by analogs of 1,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Serum 5'nucleotidase and alkaline phosphatase--highly predictive liver function tests for the diagnosis of graft-versus-host disease in bone marrow transplant recipients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Role of CTLA-4 in the activation of single- and double-positive thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404720

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404720

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508005%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference