Early Events in Peripheral Regulatory T Cell Induction via the Nasal Mucosa (Q56903755)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14568933%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Early events in peripheral regulatory T cell induction via the nasal mucosa (English)

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20 December 2019

Early Events in Peripheral Regulatory T Cell Induction via the Nasal Mucosa (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.9.4592

23 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.9.4592

23 March 2024

author name string

Femke Hauet-Broere

2

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20 December 2019

Wendy Jansen

3

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20 December 2019

Georg Kraal

5

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20 December 2019

Wendy W. J. Unger

1

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23 March 2024

Lisette A. van Berkel

4

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23 March 2024

Janneke N. Samsom

6

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23 March 2024

language of work or name

English

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publication date

1 November 2003

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full work available at URL

20 December 2019

published in

Journal of Immunology

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20 December 2019

volume

171

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20 December 2019

issue

9

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20 December 2019

page(s)

4592-4603

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Oral tolerance: immune mechanisms and treatment of autoimmune diseases

20 December 2019

cites work

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Mucosal tolerance is associated with, but independent of, up-regulation Th2 responses

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Nasal tolerance induces antigen-specific CD4+CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells

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T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen although tolerized T cells display a defect in cell division.

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Determination of lymphocyte division by flow cytometry

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T cell memory

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Certified professionals: CD4(+)CD25(+) suppressor T cells

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CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma

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Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation

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Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells

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23 March 2024

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23 March 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14568933%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference