A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase (Q56930202)

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26 January 2020

title

A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase (English)

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26 January 2020

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2

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26 January 2020

Sebastian Bonhoeffer

8

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26 January 2020

Christos J Petropoulos

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object named as

Christos J Petropoulos

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26 January 2020

author name string

Trevor Hinkley

1

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26 January 2020

Colombe Chappey

3

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26 January 2020

Mojgan Haddad

4

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26 January 2020

Eric Stawiski

5

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26 January 2020

Jeannette M Whitcomb

6

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26 January 2020

language of work or name

English

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publication date

27 March 2011

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26 January 2020

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26 January 2020

volume

43

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issue

5

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26 January 2020

page(s)

487-489

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https://scigraph.springernature.com/pub.10.1038/ng.795

26 January 2020

exact match

0 references

cites work

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1 reference

Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update

21 January 2018

1 reference

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

21 January 2018

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Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing

21 January 2018

1 reference

Extent of cross-resistance between agents used to treat human immunodeficiency virus type 1 infection in clinically derived isolates

21 January 2018

1 reference

Retracing the evolutionary pathways of human immunodeficiency virus type 1 resistance to protease inhibitors: virus fitness in the absence and in the presence of drug

21 January 2018

1 reference

Evidence for Positive Epistasis in HIV-1

21 January 2018

1 reference

The Dantzig selector: Statistical estimation when p is much larger than n

21 January 2018

1 reference

Generalized Linear Models

21 January 2018

1 reference

Rationale and uses of a public HIV drug-resistance database

21 January 2018

1 reference

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

21 January 2018

1 reference

Protein sectors: evolutionary units of three-dimensional structure

21 January 2018

1 reference

HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations

21 January 2018

1 reference

The contribution of epistasis to the architecture of fitness in an RNA virus

21 January 2018

1 reference

Positive selection detection in 40,000 human immunodeficiency virus (HIV) type 1 sequences automatically identifies drug resistance and positive fitness mutations in HIV protease and reverse transcriptase

21 January 2018

1 reference

The genetic landscape of a cell

21 January 2018

1 reference

Drug interactions and the evolution of antibiotic resistance

21 January 2018

1 reference

Epistatic buffering of fitness loss in yeast double deletion strains

21 January 2018

1 reference

Epistasis between deleterious mutations and the evolution of recombination

21 January 2018

1 reference

The evolution of sex: empirical insights into the roles of epistasis and drift

21 January 2018

1 reference

Clinical significance of human immunodeficiency virus type 1 replication fitness

21 January 2018

1 reference

Genotypic predictors of human immunodeficiency virus type 1 drug resistance

21 January 2018

1 reference

Principal component analysis of general patterns of HIV-1 replicative fitness in different drug environments.

21 January 2018

1 reference

HIV-1 drug resistance mutations: an updated framework for the second decade of HAART

21 January 2018

1 reference

12 December 2020

Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1.

1 reference

12 December 2020

1 reference

12 December 2020

Update of the Drug Resistance Mutations in HIV-1.

1 reference

12 December 2020

Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1038/NG.795

1 reference

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26 January 2020

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