Beyond pattern recognition: five immune checkpoints for scaling the microbial threat (Q56989281)

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

31 March 2020

1 reference

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

31 March 2020

1 reference

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

31 March 2020

1 reference

Pattern recognition receptors and inflammation

31 March 2020

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Regulation of adaptive immunity by the innate immune system

31 March 2020

1 reference

Nods: a family of cytosolic proteins that regulate the host response to pathogens

31 March 2020

1 reference

Nod-like receptors: sentinels at host membranes

31 March 2020

1 reference

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

31 March 2020

1 reference

Myeloid C-type lectin receptors in pathogen recognition and host defense

31 March 2020

1 reference

Pathogen recognition by the innate immune system

31 March 2020

1 reference

31 March 2020

1 reference

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

31 March 2020

1 reference

Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency

31 March 2020

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Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency

31 March 2020

1 reference

Human primary immunodeficiency diseases

31 March 2020

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Primary immunodeficiencies of protective immunity to primary infections

31 March 2020

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Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system

31 March 2020

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Failure of killed Listeria monocytogenes vaccine to produce protective immunity

31 March 2020

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Priming of memory but not effector CD8 T cells by a killed bacterial vaccine

31 March 2020

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Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria

31 March 2020

1 reference

Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'.

31 March 2020

1 reference

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

31 March 2020

1 reference

Collaboration between the innate immune receptors dectin-1, TLRs, and Nods.

31 March 2020

1 reference

Programming the magnitude and persistence of antibody responses with innate immunity

31 March 2020

1 reference

Live bacterial vaccines--a review and identification of potential hazards

31 March 2020

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Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

31 March 2020

1 reference

Immunological mechanisms of vaccination

31 March 2020

1 reference

Common themes in the design and function of bacterial effectors

31 March 2020

1 reference

The versatility of Helicobacter pylori CagA effector protein functions: The master key hypothesis

31 March 2020

1 reference

Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis

31 March 2020

1 reference

Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages

31 March 2020

1 reference

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

31 March 2020

1 reference

A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system

31 March 2020

1 reference

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

31 March 2020

1 reference

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

31 March 2020

1 reference

The role of the inflammasome in cellular responses to toxins and bacterial effectors

31 March 2020

1 reference

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

31 March 2020

1 reference

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

31 March 2020

1 reference

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

31 March 2020

1 reference

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

31 March 2020

1 reference

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

31 March 2020

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Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.

31 March 2020

1 reference

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway

31 March 2020

1 reference

Salmonella and Caspase-1: A complex Interplay of Detection and Evasion

31 March 2020

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Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

31 March 2020

1 reference

The role of intestinal endotoxin in liver injury: A long and evolving history

31 March 2020

1 reference

Recent progress in understanding the phenotype and function of intestinal dendritic cells and macrophages

31 March 2020

1 reference

Bacteria and MAMP-induced morphogenesis of the immune system

31 March 2020

1 reference

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

31 March 2020

1 reference

Surface hydrophobin prevents immune recognition of airborne fungal spores

31 March 2020

1 reference

Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display

31 March 2020

1 reference

Growth of Candida albicans hyphae

31 March 2020

1 reference

A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells.

31 March 2020

1 reference

Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo

31 March 2020

1 reference

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

31 March 2020

1 reference

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

31 March 2020

1 reference

Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome

31 March 2020

1 reference

Nonfilamentous C. albicans mutants are avirulent

31 March 2020

1 reference

Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection

31 March 2020

1 reference

Dendritic cells in intestinal immune regulation.

31 March 2020

1 reference

Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment.

31 March 2020

1 reference

Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.

31 March 2020

1 reference

The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria

31 March 2020

1 reference

IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function.

31 March 2020

1 reference

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

31 March 2020

1 reference

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

31 March 2020

1 reference

Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine

31 March 2020

1 reference

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

31 March 2020

1 reference

Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response

31 March 2020

1 reference

Induction of colonic regulatory T cells by indigenous Clostridium species

31 March 2020

1 reference

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

31 March 2020

1 reference

The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment

31 March 2020

1 reference

Induction of intestinal Th17 cells by segmented filamentous bacteria

31 March 2020

1 reference

Immune responses to commensal and environmental microbes

31 March 2020

1 reference

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria

31 March 2020

1 reference

CD11b+ Peyer’s Patch Dendritic Cells Secrete IL-6 and Induce IgA Secretion from Naive B Cells

31 March 2020

1 reference

The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

31 March 2020

1 reference

Peripheral education of the immune system by colonic commensal microbiota.

31 March 2020

1 reference

Intestinal lamina propria dendritic cell subsets have different origin and functions.

31 March 2020

1 reference

Regulation of type III secretion systems

31 March 2020

1 reference

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

31 March 2020

1 reference

Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice

31 March 2020

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Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10.

31 March 2020

1 reference

Yersinia pestis YopJ suppresses tumor necrosis factor alpha induction and contributes to apoptosis of immune cells in the lymph node but is not required for virulence in a rat model of bubonic plague

31 March 2020

1 reference

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

31 March 2020

1 reference

A clinical perspective of IL-1β as the gatekeeper of inflammation

31 March 2020

1 reference

The danger model: a renewed sense of self

31 March 2020

1 reference

Immunogenic and tolerogenic cell death

31 March 2020

1 reference

31 March 2020

1 reference

NLR functions beyond pathogen recognition

31 March 2020

1 reference

IFI16 is an innate immune sensor for intracellular DNA

31 March 2020

1 reference

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

31 March 2020

1 reference

DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells

31 March 2020

1 reference

Plant pathogens and integrated defence responses to infection

31 March 2020

1 reference

Infective endocarditis in adults

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22362354

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22362354