Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma (Q57243407)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20818440%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20818440%20AND%20SRC:MED&resulttype=core&format=json

alveolar rhabdomyosarcoma

13 February 2020

main subject

1 reference

2

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13 February 2020

Kathryn Pritchard-Jones

4

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13 February 2020

Janet Shipley

5

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13 February 2020

Simone Fulda

7

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13 February 2020

author name string

A Zibat

1

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13 February 2020

A Rosenberger

3

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13 February 2020

H Hahn

6

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13 February 2020

language of work or name

English

0 references

publication date

6 September 2010

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13 February 2020

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13 February 2020

volume

29

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13 February 2020

issue

48

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13 February 2020

page(s)

6323-6330

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Medulloblastoma growth inhibition by hedgehog pathway blockade

13 February 2020

cites work

1 reference

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

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Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion

21 January 2018

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Cooperative trial CWS-91 for localized soft tissue sarcoma in children, adolescents, and young adults

21 January 2018

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Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group

21 January 2018

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Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.368

The hedgehog regulated oncogenes Gli1 and Gli2 block myoblast differentiation by inhibiting MyoD-mediated transcriptional activation

21 January 2018

1 reference

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Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification

21 January 2018

1 reference

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Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

21 January 2018

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Rhabdomyosarcoma in children

21 January 2018

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Communicating with Hedgehogs

21 January 2018

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Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma

21 January 2018

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

21 January 2018

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Pleiotropic effects of sonic hedgehog on muscle satellite cells.

21 January 2018

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Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

21 January 2018

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Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation.

21 January 2018

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Rhabdomyosarcoma--working out the pathways

21 January 2018

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Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

21 January 2018

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Distinguishing undifferentiated embryonal sarcoma of the liver from biliary tract rhabdomyosarcoma: a Children's Oncology Group study

21 January 2018

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Increased expression of the hedgehog signaling pathway in pediatric solid malignancies

21 January 2018

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Hedgehog signalling in cancer formation and maintenance

21 January 2018

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Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

21 January 2018

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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

21 January 2018

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Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

21 January 2018

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PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

21 January 2018

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

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Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development

21 January 2018

1 reference

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Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.368

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.368

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.368

Targeting the Hedgehog pathway in cancer

21 January 2018

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Expression profiling and identification of novel genes involved in myogenic differentiation.

31 March 2020

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Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry

31 March 2020

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20818440%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference