Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress (Q57272382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15475010%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Akt phosphorylation and NFkappaB activation are counterregulated under conditions of oxidative stress (English)

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3 January 2020

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2

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3 January 2020

Paul J Hertzog

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3 January 2020

author name string

Uğur Ali

4

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3 January 2020

Juliet M Taylor

1

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3 January 2020

Jodee A Gould

3

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3 January 2020

Rocco C Iannello

6

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language of work or name

English

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publication date

1 November 2004

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Experimental Cell Research

3 January 2020

published in

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volume

300

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issue

2

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3 January 2020

page(s)

463-475

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Oxygen radicals and signaling

3 January 2020

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Redox signaling: hydrogen peroxide as intracellular messenger

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

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Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

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The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons.

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Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

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Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

7 January 2021

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Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

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The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

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FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

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Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

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Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress

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Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

7 January 2021

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

7 January 2021

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PI3K: downstream AKTion blocks apoptosis

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

7 January 2021

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

7 January 2021

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Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

7 January 2021

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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PDGF-induced Akt phosphorylation does not activate NF-kappa B in human vascular smooth muscle cells and fibroblasts

7 January 2021

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Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury.

7 January 2021

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Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

7 January 2021

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Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

7 January 2021

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The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons

7 January 2021

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Is NF-kappaB the sensor of oxidative stress?

7 January 2021

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Redox regulation of NF-kappa B activation

7 January 2021

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A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

7 January 2021

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Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

7 January 2021

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7 January 2021

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7 January 2021

Identifiers

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3 January 2020

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