Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function (Q57292225)

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24 April 2020

title

Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30257949%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

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Ramamoorthy Senthilkumar

2

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24 April 2020

Stephen L. Nutt

5

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24 April 2020

Rudolf Grosschedl

7

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24 April 2020

author name string

Virginia Andreani

1

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24 April 2020

Abhinav Pandey

3

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24 April 2020

Ekaterina Lupar

4

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24 April 2020

Tim Lämmermann

6

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24 April 2020

language of work or name

English

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publication date

26 September 2018

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Proceedings of the National Academy of Sciences of the United States of America

24 April 2020

published in

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24 April 2020

volume

115

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24 April 2020

issue

41

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24 April 2020

page(s)

E9630-E9639

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

24 April 2020

copyright license

start time

26 September 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

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Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes

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Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response

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A coordinated change in chemokine responsiveness guides plasma cell movements

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Integrin-mediated long-term B cell retention in the splenic marginal zone.

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Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response.

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The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity

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Homing of antibody secreting cells

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Cellular niches controlling B lymphocyte behavior within bone marrow during development.

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Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

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Regulation of plasma-cell development

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VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin.

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Intracellular signalling controlling integrin activation in lymphocytes

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A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4.

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Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism

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12 December 2020

Structural basis of integrin regulation and signaling

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Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

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Peripheral B cell subsets

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The endoplasmic reticulum stress response in immunity and autoimmunity

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Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

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12 December 2020

pERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulin

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12 December 2020

gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis

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12 December 2020

Calcium as a crucial cofactor for low density lipoprotein receptor folding in the endoplasmic reticulum

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12 December 2020

The cystic fibrosis-causing mutation deltaF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis.

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12 December 2020

Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone

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12 December 2020

Analysis and design of RNA sequencing experiments for identifying isoform regulation

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12 December 2020

Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells

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12 December 2020

Protein folding and modification in the mammalian endoplasmic reticulum.

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12 December 2020

Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking

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12 December 2020

The unfolded protein response: from stress pathway to homeostatic regulation

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12 December 2020

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

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12 December 2020

The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival

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12 December 2020

Differential analysis of gene regulation at transcript resolution with RNA-seq

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12 December 2020

Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes

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12 December 2020

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

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12 December 2020

MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress

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12 December 2020

Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool

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12 December 2020

The generation of antibody-secreting plasma cells.

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12 December 2020

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

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12 December 2020

c-Myb is required for plasma cell migration to bone marrow after immunization or infection

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12 December 2020

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

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12 December 2020

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

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12 December 2020

Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1809739115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30257949%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

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24 April 2020

PubMed publication ID

30257949

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