Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet (Q57591304)

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English	Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet	article

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scholarly article

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13 March 2020

Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet (English)

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13 March 2020

type 2 diabetes

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based on heuristic

inferred from title

14

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13 March 2020

author name string

Takeru Sakai

1

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13 March 2020

Toru Kusakabe

2

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13 March 2020

Ken Ebihara

3

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Daisuke Aotani

4

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Sachiko Yamamoto-Kataoka

5

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Mingming Zhao

6

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13 March 2020

Valentino Milton Junior Gumbilai

7

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13 March 2020

Chihiro Ebihara

8

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Megumi Aizawa-Abe

9

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Yuji Yamamoto

10

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13 March 2020

Michio Noguchi

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Junji Fujikura

12

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Kiminori Hosoda

13

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13 March 2020

Kazuwa Nakao

15

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publication date

26 August 2014

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13 March 2020

American Journal of Physiology - Endocrinology and Metabolism

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307

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8

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E712-9

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13 March 2020

Functional magnetic resonance imaging analysis of food-related brain activity in patients with lipodystrophy undergoing leptin replacement therapy

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Alterations in energy balance following exenatide administration

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Chronic administration of the glucagon-like peptide-1 analog, liraglutide, delays the onset of diabetes and lowers triglycerides in UCD-T2DM rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Combination of obesity and high-fat feeding diminishes sensitivity to GLP-1R agonist exendin-4.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

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https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Lipotoxicity disrupts incretin-regulated human β cell connectivity

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https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Glucagon-like peptide-1 7-36: a physiological incretin in man.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and a high-fat diet

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Leptin activates hepatic 5'-AMP-activated protein kinase through sympathetic nervous system and α1-adrenergic receptor: a potential mechanism for improvement of fatty liver in lipodystrophy by leptin

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Leptin as an adjunct of insulin therapy in insulin-deficient diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Serum Leptin Concentration, Adiposity, and Body Fat Distribution in Mexican-Americans

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Direct antidiabetic effect of leptin through triglyceride depletion of tissues.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Glucagon-like peptide-1 and islet lipolysis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Skeletal muscle AMP-activated protein kinase phosphorylation parallels metabolic phenotype in leptin transgenic mice under dietary modification

1 reference

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21 January 2018

A role for glucagon-like peptide-1 in the central regulation of feeding

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Pancreatic fat content and beta-cell function in men with and without type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Leptin therapy in insulin-deficient type I diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00272.2014

21 January 2018

Acute stimulation of glucose metabolism in mice by leptin treatment

1 reference

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21 January 2018

Identifiers

10.1152/AJPENDO.00272.2014

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13 March 2020

1 reference

Europe PubMed Central

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13 March 2020

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