In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy (Q57789781)

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English	In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy	article

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

1 reference

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cryptococcal meningitis

1 reference

based on heuristic

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Nathan Paul Wiederhold

1

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17 April 2020

Thomas F Patterson

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Thomas F Patterson

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17 April 2020

Laura K. Najvar

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Laura K Najvar

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17 April 2020

William R. Kirkpatrick

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William R Kirkpatrick

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17 April 2020

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Xin Xu

2

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17 April 2020

Amy Wang

3

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17 April 2020

Edward P Garvey

5

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17 April 2020

Elizabeth A Ottinger

6

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17 April 2020

Asaf Alimardanov

7

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17 April 2020

Jim Cradock

8

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17 April 2020

Mark Behnke

9

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17 April 2020

William J Hoekstra

10

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17 April 2020

Stephen R Brand

11

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17 April 2020

Robert J Schotzinger

12

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17 April 2020

Rosie Jaramillo

13

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17 April 2020

Marcos Olivo

14

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17 April 2020

language of work or name

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publication date

24 October 2018

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17 April 2020

Antimicrobial Agents and Chemotherapy

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17 April 2020

62

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17 April 2020

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Comparison of amphotericin B with fluconazole in the treatment of acute AIDS-associated cryptococcal meningitis. The NIAID Mycoses Study Group and the AIDS Clinical Trials Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluconazole compared with amphotericin B plus flucytosine for cryptococcal meningitis in AIDS. A randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy with fluconazole and flucytosine in the murine model of cryptococcal meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. National Institute of Allergy and Infectious Diseases Mycoses Study Group and AIDS Clinical Trials Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of severity of meningitis on fungicidal activity of flucytosine combined with fluconazole in a murine model of cryptococcal meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term outcome of AIDS-associated cryptococcosis in the era of combination antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of disease presentation and outcome during cryptococcosis: the CryptoA/D study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major role for amphotericin B-flucytosine combination in severe cryptococcosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A murine model of Cryptococcus gattii meningoencephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination antifungal therapy for cryptococcal meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and optimization of highly-selective fungal CYP51 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isavuconazole Is Effective for the Treatment of Experimental Cryptococcal Meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of VT-1129 against Cryptococcus neoformans clinical isolates with high fluconazole MICs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Fungal Cyp51 Inhibitor VT-1129 Is Efficacious in an Experimental Model of Cryptococcal Meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30104280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01315-18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30104280%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

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