The Bacterial SRP Receptor, SecA and the Ribosome Use Overlapping Binding Sites on the SecY Translocon (Q57830682)

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Victor Sourjik

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object named as

Victor Sourjik

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author name string

Patrick Kuhn

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Benjamin Weiche

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Lukas Sturm

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Erik Sommer

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Hans-Georg Koch

Signal recognition particle-dependent protein targeting, universal to all kingdoms of life

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publication date

25 February 2011

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published in

Traffic

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volume

12

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issue

5

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page(s)

563-578

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cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Signal recognition particle receptor exposes the ribosomal translocon binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Conformational changes in the bacterial SRP receptor FtsY upon binding of guanine nucleotides and SRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Multiple conformational switches in a GTPase complex control co-translational protein targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Depletion of the signal recognition particle receptor inactivates ribosomes in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Membrane protein biogenesis in Ffh- or FtsY-depleted Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

A cleavable N-terminal membrane anchor is involved in membrane binding of the Escherichia coli SRP receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Two cooperating helices constitute the lipid-binding domain of the bacterial SRP receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Recognition of a subset of signal sequences by Ssh1p, a Sec61p-related protein in the membrane of endoplasmic reticulum of yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

X-ray structure of a protein-conducting channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Membrane binding of the bacterial signal recognition particle receptor involves two distinct binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Dynamic map of protein interactions in the Escherichia coli chemotaxis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

An improved cyan fluorescent protein variant useful for FRET

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Assembly and overexpression of membrane proteins in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Substrate twinning activates the signal recognition particle and its receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Helical distribution of the bacterial chemoreceptor via colocalization with the Sec protein translocation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Efficient incorporation of unnatural amino acids into proteins in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Characterization of cold-sensitive secY mutants of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The Sec protein-translocation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SecY alterations that impair membrane protein folding and generate a membrane stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Conformational transition of Sec machinery inferred from bacterial SecYE structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SecY-SecY and SecY-SecG contacts revealed by site-specific crosslinking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Identification of a region of interaction between Escherichia coli SecA and SecY proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Structure of a complex of the ATPase SecA and the protein-translocation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Association of Escherichia coli ribosomes with the inner membrane requires the signal recognition particle receptor but is independent of the signal recognition particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Mapping ligand-receptor interfaces: approaching the resolution limit of benzophenone-based photoaffinity scanning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

In vitro studies with purified components reveal signal recognition particle (SRP) and SecA/SecB as constituents of two independent protein-targeting pathways of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The Escherichia coli SRP and SecB targeting pathways converge at the translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

A dual function for SecA in the assembly of single spanning membrane proteins in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Assembly of the translocase motor onto the preprotein-conducting channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The core Escherichia coli signal recognition particle receptor contains only the N and G domains of FtsY

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Heterodimeric GTPase Core of the SRP Targeting Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Sequence-specific interactions of nascent Escherichia coli polypeptides with trigger factor and signal recognition particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Trigger factor binds to ribosome-signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Distinct modes of signal recognition particle interaction with the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

SRbeta coordinates signal sequence release from SRP with ribosome binding to the translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Membrane binding of SRP pathway components in the halophilic archaea Haloferax volcanii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

The Haloferax volcanii FtsY homolog is critical for haloarchaeal growth but does not require the A domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Protein traffic for secretion and related machinery of Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Studies on transformation of Escherichia coli with plasmids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Naphthoquinone-dependent generation of superoxide radicals by quinone reductase isolated from the plasma membrane of soybean.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Open mass spectrometry search algorithm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

A novel proteomic screen for peptide-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Application of quantitative immunoprecipitation combined with knockdown and cross-linking to Chlamydomonas reveals the presence of vesicle-inducing protein in plastids 1 in a common complex with chloroplast HSP90C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X

Proteomic characterization of the human centrosome by protein correlation profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2011.01167.X