Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor (Q57919844)

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9 December 2019

title

Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor (English)

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9 December 2019

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3

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9 December 2019

author name string

David Boettiger

series ordinal

2

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9 December 2019

Marina A Guvakova

series ordinal

1

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9 December 2019

publication date

1 June 2002

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International Journal of Biochemistry & Cell Biology

9 December 2019

published in

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9 December 2019

volume

34

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9 December 2019

issue

6

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9 December 2019

page(s)

685-698

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Cell adhesion: the molecular basis of tissue architecture and morphogenesis

9 December 2019

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The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.

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Cell-matrix adhesions differentially regulate fascin phosphorylation

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Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42

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Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breast cancer

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Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors

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C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines

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7 January 2021

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

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7 January 2021

Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes

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Cell-adhesive responses to tenascin-C splice variants involve formation of fascin microspikes

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11943599%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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