CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13 (Q58072502)

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6 January 2020

title

CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13 (English)

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6 January 2020

1

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6 January 2020

Matthew Perugini

2

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6 January 2020

Marc Kvansakul

3

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6 January 2020

David C Huang

5

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6 January 2020

author name string

Chen L

4

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6 January 2020

Colman PM

6

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6 January 2020

publication date

1 March 2006

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Cell Death & Differentiation

6 January 2020

published in

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6 January 2020

volume

13

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6 January 2020

issue

3

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6 January 2020

page(s)

426-434

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The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

6 January 2020

cites work

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The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

21 January 2018

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

21 January 2018

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Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

21 January 2018

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Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

21 January 2018

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Role of CED-4 in the activation of CED-3.

21 January 2018

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Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors.

21 January 2018

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Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

21 January 2018

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Mutational analysis of the interacting cell death regulators CED-9 and CED-4.

21 January 2018

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Oligomerized Ced-4 kills budding yeast through a caspase-independent mechanism

21 January 2018

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Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation

21 January 2018

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Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

21 January 2018

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Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.

21 January 2018

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Unique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactions

21 January 2018

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

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Solution structure of the antiapoptotic protein bcl-2

21 January 2018

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The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

21 January 2018

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Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 January 2018

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

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Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

21 January 2018

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Structure of the apoptotic protease-activating factor 1 bound to ADP

21 January 2018

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Subcellular localization, oligomerization, and ATP-binding of Caenorhabditis elegans CED-4.

21 January 2018

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Cell surface proteins of Candida albicans: preparation of extracts and improved detection of proteins

21 January 2018

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C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

21 January 2018

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Two-promoter vector is highly efficient for overproduction of protein complexes

21 January 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

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The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease

21 January 2018

1 reference

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Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation

21 January 2018

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Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition

21 January 2018

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Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

21 January 2018

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Self-association of Human Apolipoprotein E3 and E4 in the Presence and Absence of Phospholipid

21 January 2018

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inferred from DOI database lookup

7 January 2021

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Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4401762

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6 January 2020

1 reference