Nanoparticles Escaping RES and Endosome: Challenges for siRNA Delivery for Cancer Therapy (Q58691112)

April 2022 Public Data File from Crossref

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copyrighted

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April 2022 Public Data File from Crossref

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Single processing center models for human Dicer and bacterial RNase III

21 January 2018

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

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Nonviral vectors in the new millennium: delivery barriers in gene transfer

21 January 2018

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Design and development of polymers for gene delivery

21 January 2018

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Knocking down barriers: advances in siRNA delivery

21 January 2018

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Nanoparticle-based delivery system for application of siRNA in vivo

21 January 2018

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Barriers to nonviral gene delivery

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging

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Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release.

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Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo.

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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

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Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects

21 January 2018

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Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

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Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

21 January 2018

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Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target

21 January 2018

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Phagocytic uptake and cytotoxicity of solid lipid nanoparticles (SLN) sterically stabilized with poloxamine 908 and poloxamer 407.

21 January 2018

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Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting

21 January 2018

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A Novel Family ofl-Amino Acid-Based Biodegradable Polymer−Lipid Conjugates for the Development of Long-Circulating Liposomes with Effective Drug-Targeting Capacity

21 January 2018

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Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

21 January 2018

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Protein release kinetics for core-shell hybrid nanoparticles based on the layer-by-layer assembly of alginate and chitosan on liposomes

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Comparison of polymerically stabilized PEG-grafted liposomes and physically adsorbed carboxymethylchitin and carboxymethyl/glycolchitin liposomes for biological applications.

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Nanoparticles evading the reticuloendothelial system: role of the supported bilayer

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Stealth nanoparticles: high density but sheddable PEG is a key for tumor targeting

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Pharmacokinetics and biodistribution of nanoparticles

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Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA.

21 January 2018

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Stabilized plasmid-lipid particles: construction and characterization

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Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection

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Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

21 January 2018

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The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 January 2018

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

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Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery

21 January 2018

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

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Targeted gene silencing using RGD-labeled chitosan nanoparticles

21 January 2018

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A multifunctional PEI-based cationic polyplex for enhanced systemic p53-mediated gene therapy

21 January 2018

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An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Target-specific gene silencing by siRNA plasmid DNA complexed with folate-modified poly(ethylenimine).

21 January 2018

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Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery

21 January 2018

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Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo

21 January 2018

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"SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers

21 January 2018

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Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG-lipids

21 January 2018

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Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides

21 January 2018

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Sheddable coatings for long-circulating nanoparticles

21 January 2018

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Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid

21 January 2018

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

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Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

21 January 2018

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Evasion of the Accelerated Blood Clearance Phenomenon by Coating of Nanoparticles with Various Hydrophilic Polymers

21 January 2018

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Effects of cleavable PEG-cholesterol derivatives on the accelerated blood clearance of PEGylated liposomes

21 January 2018

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Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production

21 January 2018

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

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A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

21 January 2018

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RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

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Bioreducible poly(amido amine)s with oligoamine side chains: synthesis, characterization, and structural effects on gene delivery

21 January 2018

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Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules

21 January 2018

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Targeted charge-reversal nanoparticles for nuclear drug delivery

21 January 2018

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Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery.

21 January 2018

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Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity

21 January 2018

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Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

pH-sensitive polymers that enhance intracellular drug delivery in vivo

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

The design and synthesis of polymers for eukaryotic membrane disruption.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

A pH-sensitive polymer that enhances cationic lipid-mediated gene transfer

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Development of a novel endosomolytic diblock copolymer for siRNA delivery

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

pH-responsive polymeric micelle carriers for siRNA drugs

21 January 2018

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Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy

21 January 2018

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Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine.

21 January 2018

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Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery

21 January 2018

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A highly efficient siRNA carrier of PBLG modified hyperbranched PEI.

21 January 2018

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Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

A biodegradable amphiphilic and cationic triblock copolymer for the delivery of siRNA targeting the acid ceramidase gene for cancer therapy.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

21 January 2018

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Acid-transforming polypeptide micelles for targeted nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Controlled delivery of plasmid DNA and siRNA to intracellular targets using ketalized polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Combined multimodal optical imaging and targeted gene silencing using stimuli-transforming nanotheragnostics

21 January 2018

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Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery

21 January 2018

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Lipid-based systemic delivery of siRNA.

21 January 2018

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Lipid-based nanotherapeutics for siRNA delivery

21 January 2018

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Lipidic systems for in vivo siRNA delivery

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo

21 January 2018

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Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery

21 January 2018

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Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer.

21 January 2018

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Nanoparticles targeted with NGR motif deliver c-myc siRNA and doxorubicin for anticancer therapy

21 January 2018

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Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles

21 January 2018

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Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery

21 January 2018

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Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer

21 January 2018

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Carbonate apatite-facilitated intracellularly delivered siRNA for efficient knockdown of functional genes

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Magnesium phosphate nanoparticles can be efficiently used in vitro and in vivo as non-viral vectors for targeted gene delivery

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Calcium carbonate nanoparticle delivering vascular endothelial growth factor-C siRNA effectively inhibits lymphangiogenesis and growth of gastric cancer in vivo

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

21 January 2018

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A new gene delivery formulation of polyethylenimine/DNA complexes coated with PEG conjugated fusogenic peptide

21 January 2018

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GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery

21 January 2018

1 reference

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A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Membrane-active peptides for non-viral gene therapy: making the safest easier.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Rational design of cationic lipids for siRNA delivery

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

Multiple lipid compartments slow vesicle contents release in lipases and serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia

21 January 2018

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Formulation of photocleavable liposomes and the mechanism of their content release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Mechanistic studies of the triggered release of liposomal contents by matrix metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1155%2F2011%2F742895

A reducible polycationic gene vector derived from thiolated low molecular weight branched polyethyleneimine linked by 2-iminothiolane

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Polyelectrolyte Multilayers Fabricated from 'Charge-Shifting' Anionic Polymers: A New Approach to Controlled Film Disruption and the Release of Cationic Agents from Surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Pore-forming peptides induce rapid phospholipid flip-flop in membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

pH-dependent bilayer destabilization by an amphipathic peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Membrane-destabilizing polyanions: interaction with lipid bilayers and endosomal escape of biomacromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Proton-actuated membrane-destabilizing polyion complex micelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Degradable, pH-sensitive, membrane-destabilizing, comb-like polymers for intracellular delivery of nucleic acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Synthesis of novel cationic lipids having polyamidoamine dendrons and their transfection activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly(2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895

Controlled cytoplasmic and nuclear localization of plasmid DNA and siRNA by differentially tailored polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F742895