Autoantibodies enhance agonist action and binding to cardiac muscarinic receptors in chronic Chagas' disease (Q58844793)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702010%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Autoantibodies enhance agonist action and binding to cardiac muscarinic receptors in chronic Chagas' disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702010%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

Antonio Campos de Carvalho

7

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12 January 2020

author name string

Ciria C Hernandez

1

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12 January 2020

Jose H Nascimento

2

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12 January 2020

Elen A Chaves

3

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12 January 2020

Patricia C Costa

4

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12 January 2020

Masako O Masuda

5

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12 January 2020

Eleonora Kurtenbach

6

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12 January 2020

Luis E Gimenez

8

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12 January 2020

language of work or name

English

0 references

publication date

1 January 2008

1 reference

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Journal of Receptors and Signal Transduction

12 January 2020

published in

1 reference

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12 January 2020

volume

28

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12 January 2020

issue

4

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12 January 2020

page(s)

375-401

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DNA immunizations with M2 muscarinic and beta1 adrenergic receptor coding plasmids impair cardiac function in mice.

12 January 2020

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1 reference

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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Views on the autoimmunity hypothesis for Chagas disease pathogenesis

30 November 2018

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Human chagasic IgGs bind to cardiac muscarinic receptors and impair L-type Ca2+ currents

30 November 2018

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Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin

30 November 2018

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Structure and activation of muscarinic acetylcholine receptors

30 November 2018

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Therapeutic use of muscarinic acetylcholine receptor peptide to prevent mice chagasic cardiac dysfunction

30 November 2018

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30 November 2018

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G protein-coupled receptor allosterism and complexing

30 November 2018

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Beneficial effect of muscarinic-2 antagonist on dilated cardiomyopathy induced by autoimmune mechanism against muscarinic-2 receptor.

30 November 2018

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Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors

30 November 2018

1 reference

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Multiple allosteric sites on muscarinic receptors

30 November 2018

1 reference

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30 November 2018

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Differential profile and biochemical effects of antiautonomic membrane receptor antibodies in ventricular arrhythmias and sinus node dysfunction

30 November 2018

1 reference

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Autoantibodies against the beta- and muscarinic receptors in cardiomyopathy

30 November 2018

1 reference

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Sera from chronic chagasic patients depress cardiac electrogenesis and conduction

30 November 2018

1 reference

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

30 November 2018

1 reference

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Cardiac M(2) muscarinic cholinoceptor activation by human chagasic autoantibodies: association with bradycardia

30 November 2018

1 reference

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Subtype-selective positive cooperative interactions between brucine analogs and acetylcholine at muscarinic receptors: functional studies

30 November 2018

1 reference

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Functionally active cardiac antibodies in chronic Chagas' disease are specifically blocked by Trypanosoma cruzi antigens

30 November 2018

1 reference

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Interaction of Mg2+ with the allosteric site of muscarinic M2 receptors.

30 November 2018

1 reference

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Allosteric interactions at muscarinic cholinoceptors

30 November 2018

1 reference

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Sera from chronic chagasic patients with complex cardiac arrhythmias depress electrogenesis and conduction in isolated rabbit hearts

30 November 2018

1 reference

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Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors

30 November 2018

1 reference

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Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors.

30 November 2018

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Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes

30 November 2018

1 reference

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Interaction of human chagasic IgG with the second extracellular loop of the human heart muscarinic acetylcholine receptor: functional and pathological implications

30 November 2018

1 reference

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Structural and functional analysis of the B cell epitopes recognized by anti-receptor autoantibodies in patients with Chagas' disease

30 November 2018

1 reference

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Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor

30 November 2018

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Identification of antibodies with muscarinic cholinergic activity in human Chagas' disease: pathological implications

30 November 2018

1 reference

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Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors

30 November 2018

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Molecular mimicry between the immunodominant ribosomal protein P0 of Trypanosoma cruzi and a functional epitope on the human beta 1-adrenergic receptor

30 November 2018

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Potentiation by alcuronium of the antimuscarinic effect of N-methylscopolamine in guinea pig left atria

30 November 2018

1 reference

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Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.

30 November 2018

1 reference

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Analysis of competitive agonist-antagonist interactions by nonlinear regression.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659458

Life expectancy analysis in patients with Chagas' disease: prognosis after one decade (1973-1983)

30 November 2018

1 reference

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Site-directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function

30 November 2018

1 reference

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Allosteric antagonists of the muscarinic acetylcholine receptor

30 November 2018

1 reference

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Allosteric regulation of cloned m1–m5 muscarinic receptor subtypes

30 November 2018

1 reference

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Chagasic IgG binding with cardiac muscarinic cholinergic receptors modifies cholinergic-mediated cellular transmembrane signals

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659458

The inhibitory effect of gallamine on muscarinic receptors

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659458

The functional role of the binding site aspartate in muscarinic acetylcholine receptors, probed by site-directed mutagenesis

30 November 2018

1 reference

12 December 2020

Search for lead structures to develop new allosteric modulators of muscarinic receptors

1 reference

12 December 2020

Modification of the binding properties of muscarinic receptors by gallamine

1 reference

12 December 2020

Two allosteric modulators interact at a common site on cardiac muscarinic receptors

1 reference

12 December 2020

Site-directed mutagenesis on the m2 muscarinic acetylcholine receptor: the significance of Tyr403 in the binding of agonists and functional coupling

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12 December 2020

Immunochemical and functional characterization of an agonist-like monoclonal antibody against the M2 acetylcholine receptor

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12 December 2020

Myocardial injury due to G-protein coupled receptor-autoimmunity

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12 December 2020

Divergent modes of action among cationic allosteric modulators of muscarinic M2 receptors

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12 December 2020

10.1080/10799890802262319

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702010%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702010%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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