The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure (Q59353120)

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English	The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure	article

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21 April 2020

The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure (English)

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21 April 2020

protein structure

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Sudan ebolavirus

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Sudan ebolavirus

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21 April 2020

Francoise Debart

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21 April 2020

Jean-Jacques Vasseur

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21 April 2020

Etienne Decroly

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21 April 2020

Jonathan Grimes

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Jonathan M Grimes

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21 April 2020

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Baptiste Martin

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21 April 2020

Bruno Coutard

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21 April 2020

Théo Guez

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21 April 2020

Guido C Paesen

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21 April 2020

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1 September 2018

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21 April 2020

Nucleic Acids Research

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21 April 2020

46

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21 April 2020

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21 April 2020

7902-7912

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21 April 2020

copyright license

Creative Commons Attribution-NonCommercial 4.0 International

12 July 2018

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April 2022 Public Data File from Crossref

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Novel initiation of RNA synthesis in vitro by vesicular stomatitis virus

1 reference

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12 December 2020

based on heuristic

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The 5′ terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus

1 reference

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Two methyltransferase activities in the purified virions of vesicular stomatitis virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Capping of eucaryotic mRNAs

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Sequence comparison of five polymerases (L proteins) of unsegmented negative-strand RNA viruses: theoretical assignment of functional domains

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Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus

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Ebola protein analyses for the determination of genetic organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

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The structure of the 5' terminal cap of the respiratory syncytial virus mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

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Nucleic acids structure and recognition.

1 reference

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12 December 2020

based on heuristic

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Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

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Synthetic substrate analogs for the RNA-editing adenosine deaminase ADAR-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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In silico identification, structure prediction and phylogenetic analysis of the 2'-O-ribose (cap 1) methyltransferase domain in the large structural protein of ssRNA negative-strand viruses

1 reference

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An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

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The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

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Viral RNA-polymerases -- a predicted 2'-O-ribose methyltransferase domain shared by all Mononegavirales

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

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Active site in RrmJ, a heat shock-induced methyltransferase

1 reference

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Structure and mechanism of mRNA cap (guanine-N7) methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Sendai virus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus-specific mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Amino acid residues within conserved domain VI of the vesicular stomatitis virus large polymerase protein essential for mRNA cap methyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Alternate capping mechanisms for transcription of spring viremia of carp virus: evidence for independent mRNA initiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

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Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

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High-yield production of short GpppA- and 7MeGpppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2'O positions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and Function of Flavivirus NS5 Methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

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Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

1 reference

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12 December 2020

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Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A base-labile group for 2'-OH protection of ribonucleosides: a major challenge for RNA synthesis

1 reference

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Ribose 2'-O Methylation of the Vesicular Stomatitis Virus mRNA Cap Precedes and Facilitates Subsequent Guanine-N-7 Methylation by the Large Polymerase Protein

1 reference

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Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus

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The HR motif in the RNA-dependent RNA polymerase L protein of Chandipura virus is required for unconventional mRNA-capping activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus

1 reference

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1 reference

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation

1 reference

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Biochemical and genetic characterization of dengue virus methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

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2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

1 reference

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Chemical synthesis of RNA with base-labile 2'-o-(pivaloyloxymethyl)-protected ribonucleoside phosphoramidites

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

inferred from PubMed ID database lookup

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

1 reference

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Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

1 reference

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based on heuristic

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1 reference

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1 reference

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based on heuristic

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

inferred from PubMed ID database lookup

2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Taxonomy of the order Mononegavirales: update 2016

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

inferred from PubMed ID database lookup

The Zika virus methyltransferase: structure and functions for drug design perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/30192980

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based on heuristic

inferred from PubMed ID database lookup

Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Filovirus proteins for antiviral drug discovery: Structure/function bases of the replication cycle

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

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1 reference

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10.1093/NAR/GKY637

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21 April 2020

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21 April 2020

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21 April 2020

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