Population Pharmacokinetic Modeling of trans-Resveratrol and Its Glucuronide and Sulfate Conjugates After Oral and Intravenous Administration in Rats (Q59651786)

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scientific article published on 23 March 2011

Language	Label	Description	Also known as
English	Population Pharmacokinetic Modeling of trans-Resveratrol and Its Glucuronide and Sulfate Conjugates After Oral and Intravenous Administration in Rats	scientific article published on 23 March 2011

Statements

scholarly article

1 reference

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26 January 2020

Population pharmacokinetic modeling of trans-resveratrol and its glucuronide and sulfate conjugates after oral and intravenous administration in rats (English)

1 reference

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26 January 2020

pharmacokinetics

1 reference

based on heuristic

inferred from title

5

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26 January 2020

author name string

Helena Colom

1

1 reference

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26 January 2020

Irene Alfaras

2

1 reference

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26 January 2020

Mònica Maijó

3

1 reference

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26 January 2020

M Emília Juan

4

1 reference

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26 January 2020

publication date

23 March 2011

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26 January 2020

Pharmaceutical Research

1 reference

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26 January 2020

28

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26 January 2020

1606-1621

1 reference

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26 January 2020

7

1 reference

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26 January 2020

Resveratrol bioavailability and toxicity in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of trans-resveratrol and its metabolites in rat plasma and tissues by HPLC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol Is Absorbed in the Small Intestine as Resveratrol Glucuronide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and Disposition of Resveratrol in the Isolated Perfused Rat Liver: Role of Mrp2 in the Biliary Excretion of Glucuronides

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol: its biologic targets and functional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicogenomics of resveratrol in rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of breast cancer resistance protein (BCRP1/ABCG2) in the bioavailability and tissue distribution of trans-resveratrol in knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol: a natural polyphenol with multiple chemopreventive properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of resveratrol bioavailability in the perfused small intestine of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21431452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-011-0395-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21431452%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21431452%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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