Novel application of trimethyl chitosan as an adjuvant in vaccine delivery (Q59812625)

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13 April 2020

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26 October 2020

11 December 2020

Novel application of trimethyl chitosan as an adjuvant in vaccine delivery (English)

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13 April 2020

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macromolecular substance

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author name string

Manish Gupta

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13 April 2020

Vatika Gupta

3

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13 April 2020

Himanshu Gogoi

4

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13 April 2020

Rakesh Bhatnagar

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language of work or name

English

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publication date

23 November 2018

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International Journal of Nanomedicine

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20 June 2019

25 June 2019

16 November 2019

18 November 2019

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26 October 2020

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Creative Commons Attribution-NonCommercial

13 April 2020

copyright license

8 references

20 June 2019

25 June 2019

16 November 2019

18 November 2019

1 June 2020

2 October 2020

26 October 2020

11 December 2020

Dextran sulphate: an adjuvant for cell-mediated immune responses

1 reference

12 December 2020

Oral immunization with bacterial polysaccharide and adjuvant enhances antigen-specific pulmonary secretory antibody response and resistance to pneumonia

1 reference

12 December 2020

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

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12 December 2020

The biological activities of mannans and related complex carbohydrates

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12 December 2020

Macrophage activation with multi-porous beads prepared from partially deacetylated chitin

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12 December 2020

Comparison of tissue reactions produced by Haemophilus pleuropneumoniae vaccines made with six different adjuvants in swine

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12 December 2020

Adjuvant influenza vaccines

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12 December 2020

Studies on the toxicities of aluminium hydroxide and calcium phosphate as immunological adjuvants for vaccines

1 reference

12 December 2020

Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells

1 reference

12 December 2020

N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: in vitro evaluation in intestinal epithelial cells (Caco-2).

1 reference

12 December 2020

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

1 reference

12 December 2020

Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.

1 reference

12 December 2020

Viral recombinant vaccines to the E6 and E7 antigens of HPV-16

1 reference

12 December 2020

Anti-ulcer effects of chitin and chitosan, healthy foods, in rats

1 reference

12 December 2020

Immunological concepts of vaccine adjuvant activity

1 reference

12 December 2020

Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine

1 reference

12 December 2020

Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride

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12 December 2020

N-trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells

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12 December 2020

Virosomal adjuvanted antigen delivery systems

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12 December 2020

Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system

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12 December 2020

Chitosan microspheres as a potential carrier for drugs

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12 December 2020

Inulin-derived adjuvants efficiently promote both Th1 and Th2 immune responses

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12 December 2020

Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system

1 reference

12 December 2020

A special report on the chitosan-based hemostatic dressing: experience in current combat operations.

1 reference

12 December 2020

Toll or toll-free adjuvant path toward the optimal vaccine development

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12 December 2020

N,N,N-Trimethylchitosan chloride as a gene vector: synthesis and application.

1 reference

12 December 2020

Chitosan and trimethyl chitosan chloride (TMC) as adjuvants for inducing immune responses to ovalbumin in mice following nasal administration

1 reference

12 December 2020

In vitro and in vivo study of N-trimethyl chitosan nanoparticles for oral protein delivery

1 reference

12 December 2020

Dietary pulverized konjac glucomannan prevents the development of allergic rhinitis-like symptoms and IgE response in mice

1 reference

12 December 2020

Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan

1 reference

12 December 2020

Mono-N-carboxymethyl chitosan (MCC) and N-trimethyl chitosan (TMC) nanoparticles for non-invasive vaccine delivery.

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12 December 2020

Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery

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12 December 2020

Physicochemical and immunological characterization of N,N,N-trimethyl chitosan-coated whole inactivated influenza virus vaccine for intranasal administration

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12 December 2020

Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination

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12 December 2020

Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine

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12 December 2020

TMC-MCC (N-trimethyl chitosan-mono-N-carboxymethyl chitosan) nanocomplexes for mucosal delivery of vaccines.

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12 December 2020

Biodegradation, biodistribution and toxicity of chitosan

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12 December 2020

Mucosal adjuvant activity of oligomannose-coated liposomes for nasal immunization

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12 December 2020

Efficient induction of immune responses through intradermal vaccination with N-trimethyl chitosan containing antigen formulations.

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12 December 2020

Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen.

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12 December 2020

Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine

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12 December 2020

Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine

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12 December 2020

Cross-protection against influenza virus infection by intranasal administration of M2-based vaccine with chitosan as an adjuvant

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12 December 2020

Comparison of adjuvant efficacy of chitosan and aluminum hydroxide for intraperitoneally administered inactivated influenza H5N1 vaccine

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12 December 2020

Microneedle-based transcutaneous immunisation in mice with N-trimethyl chitosan adjuvanted diphtheria toxoid formulations

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12 December 2020

Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination.

1 reference

12 December 2020

In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery

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12 December 2020

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.

1 reference

12 December 2020

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

1 reference

12 December 2020

Cross-protection against influenza virus infection by intranasal administration of M1-based vaccine with chitosan as an adjuvant

1 reference

12 December 2020

Preparation of N-trimethyl chitosan-protein nanoparticles intended for vaccine delivery

1 reference

12 December 2020

Galactomannan from Caesalpinia spinosa induces phenotypic and functional maturation of human dendritic cells.

1 reference

12 December 2020

Chitosan as an adjuvant for poliovaccine

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12 December 2020

Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation.

1 reference

12 December 2020

Influenza virosomes as a vaccine adjuvant and carrier system

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12 December 2020

Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate.

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12 December 2020

Delta inulin polysaccharide adjuvant enhances the ability of split-virion H5N1 vaccine to protect against lethal challenge in ferrets

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12 December 2020

Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice

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12 December 2020

Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination

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12 December 2020

Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects

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12 December 2020

A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine

1 reference

12 December 2020

Adjuvanted, antigen loaded N-trimethyl chitosan nanoparticles for nasal and intradermal vaccination: adjuvant- and site-dependent immunogenicity in mice

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12 December 2020

PLGA, PLGA-TMC and TMC-TPP nanoparticles differentially modulate the outcome of nasal vaccination by inducing tolerance or enhancing humoral immunity

1 reference

12 December 2020

Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems

1 reference

12 December 2020

Hepatitis B surface antigen nanoparticles coated with chitosan and trimethyl chitosan: Impact of formulation on physicochemical and immunological characteristics

1 reference

12 December 2020

Chitin, chitosan, and glycated chitosan regulate immune responses: the novel adjuvants for cancer vaccine

1 reference

12 December 2020

Malaria vaccine adjuvants: latest update and challenges in preclinical and clinical research.

1 reference

12 December 2020

Alginate nanoparticles as a promising adjuvant and vaccine delivery system.

1 reference

12 December 2020

Chitosan: a promising safe and immune-enhancing adjuvant for intranasal vaccines

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12 December 2020

N,N,N-Trimethyl chitosan nanoparticles for controlled intranasal delivery of HBV surface antigen.

1 reference

12 December 2020

Antigen-conjugated N-trimethylaminoethylmethacrylate chitosan nanoparticles induce strong immune responses after nasal administration

1 reference

12 December 2020

Paclitaxel-loaded trimethyl chitosan-based polymeric nanoparticle for the effective treatment of gastroenteric tumors

1 reference

12 December 2020

Immunogenicity and safety of Advax™, a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen: a randomized controlled Phase 1 study

1 reference

12 December 2020

GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity

1 reference

12 December 2020

Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma

1 reference

12 December 2020

Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity.

1 reference

12 December 2020

Chitosan as an adjuvant for a Helicobacter pylori therapeutic vaccine

1 reference

12 December 2020

Layer-by-Layer Assembly of Inactivated Poliovirus and N-Trimethyl Chitosan on pH-Sensitive Microneedles for Dermal Vaccination

1 reference

12 December 2020

Enteric trimethyl chitosan nanoparticles containing hepatitis B surface antigen for oral delivery

1 reference

12 December 2020

Chitosan-based mucosal adjuvants: Sunrise on the ocean

1 reference

12 December 2020

Immunogenic Properties of a BCG Adjuvanted Chitosan Nanoparticle-Based Dengue Vaccine in Human Dendritic Cells

1 reference

12 December 2020

Survey of Omp19 immunogenicity against Brucella abortus and Brucella melitensis: influence of nanoparticulation versus traditional immunization

1 reference

12 December 2020

PLGA/DPPC/trimethylchitosan spray-dried microparticles for the nasal delivery of ropinirole hydrochloride: in vitro, ex vivo and cytocompatibility assessment

1 reference

12 December 2020

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

1 reference

12 December 2020

Chitosan: An Adjuvant with an Unanticipated STING.

1 reference

12 December 2020

"The Good, the Bad and the Ugly" of Chitosans

1 reference

12 December 2020

Immunization against HTLV-I with chitosan and tri-methylchitosan nanoparticles loaded with recombinant env23 and env13 antigens of envelope protein gp46.

1 reference

12 December 2020

Biological evaluation of N-2-hydroxypropyl trimethyl ammonium chloride chitosan as a carrier for the delivery of live Newcastle disease vaccine.

1 reference

12 December 2020

Intranasal Administration of Chitosan Against Influenza A (H7N9) Virus Infection in a Mouse Model

1 reference

12 December 2020

Highly Immunogenic Trimethyl Chitosan-based Delivery System for Intranasal Lipopeptide Vaccines against Group A Streptococcus

1 reference

12 December 2020

Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model.

1 reference

12 December 2020

Responses of primary human nasal epithelial cells to EDIII-DENV stimulation: the first step to intranasal dengue vaccination

1 reference

12 December 2020

Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses

1 reference

12 December 2020

Conjugation with an Inulin-Chitosan Adjuvant Markedly Improves the Immunogenicity of Mycobacterium tuberculosis CFP10-TB10.4 Fusion Protein.

1 reference

12 December 2020

N,N,N-Trimethyl chitosan: An advanced polymer with myriad of opportunities in nanomedicine

1 reference

12 December 2020

Aluminium in brain tissue in familial Alzheimer's disease

1 reference

12 December 2020

Beta-Glucan Particles as Vaccine Adjuvant Carriers.

1 reference

12 December 2020

Synthesis and Immunological Studies of the Lipomannan Backbone Glycans Found on the Surface of Mycobacterium tuberculosis

1 reference

12 December 2020

Diphtheria toxoid and N-trimethyl chitosan layer-by-layer coated pH-sensitive microneedles induce potent immune responses upon dermal vaccination in mice.

1 reference

12 December 2020

Quaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administration.

1 reference

12 December 2020

Oral immunization of mice with Omp31-loaded N-trimethyl chitosan nanoparticles induces high protection against Brucella melitensis infection.

1 reference

12 December 2020

Trimethyl Chitosan Nanoparticles Encapsulated Protective Antigen Protects the Mice Against Anthrax.

1 reference

12 December 2020

Identifiers

DOI

10.2147/IJN.S165876

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30538470%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30538470%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

30538470

1 reference