Activity of the anti-HIV agent 9-(2-phosphonyl-methoxyethyl)-2,6-diaminopurine against cytomegalovirus in vitro and in vivo (Q60221039)

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11 October 2019

title

Activity of the anti-HIV agent 9-(2-phosphonyl-methoxyethyl)-2,6-diaminopurine against cytomegalovirus in vitro and in vivo (English)

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11 October 2019

1

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11 October 2019

author name string

F Stals

series ordinal

2

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11 October 2019

C Bruggeman

series ordinal

3

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11 October 2019

E De Clercq

series ordinal

4

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11 October 2019

publication date

1 June 1993

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European Journal of Clinical Microbiology & Infectious Diseases

11 October 2019

published in

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11 October 2019

volume

12

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11 October 2019

issue

6

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11 October 2019

page(s)

437-446

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Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine

11 October 2019

cites work

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12 December 2020

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice

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12 December 2020

Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo

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12 December 2020

Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys

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12 December 2020

Isolation of a cytomegalovirus-like agent from wild rats

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12 December 2020

Congenital cytomegalovirus infection: The relative importance of primary and recurrent maternal infection

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12 December 2020

9-(2-Phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys

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12 December 2020

Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents

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12 December 2020

A novel selective broad-spectrum anti-DNA virus agent

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12 December 2020

Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

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12 December 2020

Impact of cytomegalovirus infection on organ transplant recipients

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12 December 2020

Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo

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12 December 2020

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice

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12 December 2020

Progressive disease due to ganciclovir-resistant cytomegalovirus in immunocompromised patients

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12 December 2020

Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).

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12 December 2020

Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent

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12 December 2020

Value of animal models to evaluate agents with potential activity against human cytomegalovirus

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12 December 2020

Inhibitory effects of 9-(2-phosphonylmethoxyethyl)adenine and 3'-azido-2',3'-dideoxythymidine on tumor development in mice inoculated intracerebrally with Moloney murine sarcoma virus

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12 December 2020

Detection of immediate early, early and late antigens of human cytomegalovirus by flow cytometry

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12 December 2020

Sexually Transmitted Diseases in Mothers of Neonates with Congenital Cytomegalovirus Infection

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12 December 2020

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro

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12 December 2020

Pediatric cytomegalovirus infection

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12 December 2020

Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine

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12 December 2020

9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections

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12 December 2020

Cytomegalovirus isolate resistant to ganciclovir and foscarnet from a marrow transplant patient

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12 December 2020

Effective chemotherapy of equine herpesvirus 1 by phosphonylmethoxyalkyl derivatives of adenine demonstrated in a novel murine model for the disease

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12 December 2020

Prevalence of Resistance in Patients Receiving Ganciclovir for Serious Cytomegalovirus Infection

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12 December 2020

Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound

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12 December 2020

Single-dose administration of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the prophylaxis of retrovirus infection in vivo

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12 December 2020

Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines

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12 December 2020

9-(2-Phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP): a novel agent with anti-human immunodeficiency virus activity in vitro and potent anti-Moloney murine sarcoma virus activity in vivo

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12 December 2020

Cytomegalovirus and the acquired immunodeficiency syndrome

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12 December 2020

Human cytomegalovirus. III. Virus-induced DNA polymerase

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12 December 2020

(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication

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12 December 2020

Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered

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12 December 2020

Inhibitory effects of acyclic nucleoside phosphonate analogs, including (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, on Epstein-Barr virus replication

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12 December 2020

Efficacy of oral 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the treatment of retrovirus and cytomegalovirus infections in mice

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12 December 2020

A severe combined immunodeficiency mutation in the mouse

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12 December 2020

(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine in the therapy of thymidine kinase-positive and -deficient herpes simplex virus experimental keratitis

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12 December 2020

Treatment of cytomegalovirus disease

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12 December 2020

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice

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12 December 2020

Early therapy of feline leukemia virus infection (FeLV-FAIDS) with 9-(2-phosphonylmethoxyethyl)adenine (PMEA)

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12 December 2020

Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine

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12 December 2020

Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice

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12 December 2020

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir

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12 December 2020

Identifiers

DOI

10.1007/BF01967438

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11 October 2019

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