Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients (Q60297012)

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English	Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients	article

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7 February 2020

Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients (English)

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7 February 2020

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7 February 2020

Branka Popović

8

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7 February 2020

author name string

Biljana Jekic

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7 February 2020

Ljiljana Lukovic

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7 February 2020

Vera Bunjevacki

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7 February 2020

Vera Milic

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7 February 2020

Ivana Novakovic

5

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7 February 2020

Tatjana Damnjanovic

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7 February 2020

Nela Maksimovic

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7 February 2020

Nemanja Damjanov

10

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7 February 2020

Goran Radunovic

11

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7 February 2020

Ljiljana Kovacevic

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7 February 2020

Maja Krajinovic

13

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7 February 2020

publication date

5 July 2012

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7 February 2020

European Journal of Clinical Pharmacology

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7 February 2020

69

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7 February 2020

3

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7 February 2020

377-383

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7 February 2020

https://scigraph.springernature.com/pub.10.1007/s00228-012-1341-3

0 references

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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The Disease Activity Score and the EULAR response criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

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Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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CCND1 G870A polymorphism contributes to breast cancer susceptibility: a meta-analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Effect of age on the efficacy and tolerance of methotrexate in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternate splicing produces a novel cyclin D1 transcript

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Factors associated with toxicity, final dose, and efficacy of methotrexate in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of action of methotrexate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1 phase progression: cycling on cue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of single nucleotide polymorphisms in the human γ-glutamyl hydrolase gene and characterization of promoter polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamation of methotrexate. Is methotrexate a prodrug?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of CCND1 A870G polymorphism in patients with advanced uterine cervical carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cyclin D1 overexpression on drug sensitivity in a human fibrosarcoma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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The influence of cyclin D1 (CCND1) 870A>G polymorphism and CCND1-thymidylate synthase (TS) gene-gene interaction on the outcome of childhood acute lymphoblastic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of genes from influx-metabolism-efflux pathway and their influence on methotrexate efficacy in rheumatoid arthritis patients among Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

based on heuristic

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Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5'-terminal Regulatory Region of the Human Gene for Thymidylate Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22763757

12 December 2020

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10.1007/S00228-012-1341-3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22763757%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22763757%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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