Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain (Q60679661)

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23 December 2019

title

Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain (English)

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23 December 2019

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23 December 2019

Victoria Chapman

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23 December 2019

author name string

Maulik D Jhaveri

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23 December 2019

Denise Richardson

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23 December 2019

David A Kendall

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23 December 2019

language of work or name

English

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publication date

1 December 2006

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23 December 2019

published in

Journal of Neuroscience

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23 December 2019

volume

26

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23 December 2019

issue

51

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23 December 2019

page(s)

13318-13327

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Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase

23 December 2019

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The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain

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CB1 receptor mediated analgesia from the Nucleus Reticularis Gigantocellularis pars alpha is activated in an animal model of neuropathic pain

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Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance

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Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

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Endocannabinoid hydrolases

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'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice

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Modulation of anxiety through blockade of anandamide hydrolysis

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Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain.

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Increased Expression of Vanilloid Receptor 1 on Myelinated Primary Afferent Neurons Contributes to the Antihyperalgesic Effect of Capsaicin Cream in Diabetic Neuropathic Pain in Mice

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Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase

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Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat.

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An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

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Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats

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Participation of the opioid system in cannabinoid-induced antinociception and emotional-like responses

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N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase

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Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry

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Oxidative metabolism of endocannabinoids by COX-2.

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Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes.

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Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat.

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12 December 2020

Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia

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Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury

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12 December 2020

Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity

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12 December 2020

Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain

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12 December 2020

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation.

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12 December 2020

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

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12 December 2020

Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels

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12 December 2020

An endocannabinoid mechanism for stress-induced analgesia.

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12 December 2020

Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat-evoked responses of dorsal horn neurons in naïve, carrageenan-inflamed and neuropathic rats

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12 December 2020

Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats

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12 December 2020

Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors

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12 December 2020

Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

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12 December 2020

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

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12 December 2020

Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages

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12 December 2020

A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats

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12 December 2020

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid typ

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12 December 2020

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models

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12 December 2020

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

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12 December 2020

Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines

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12 December 2020

The potency of the fatty acid amide hydrolase inhibitor URB597 is dependent upon the assay pH.

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12 December 2020

Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry

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12 December 2020

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12 December 2020

Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide

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12 December 2020

Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization

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12 December 2020

Quantitative assessment of tactile allodynia in the rat paw

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12 December 2020

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12 December 2020

Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’

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12 December 2020

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

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12 December 2020

SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice

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12 December 2020

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12 December 2020

The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain

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12 December 2020

Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia.

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12 December 2020

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Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6.

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12 December 2020

Control of pain initiation by endogenous cannabinoids.

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Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity

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Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors

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12 December 2020

10.1523/JNEUROSCI.3326-06.2006

Identifiers

DOI

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23 December 2019

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23 December 2019

PubMed publication ID

17182782

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