The Role of Zinc and Zinc Homeostasis in Macrophage Function (Q60912756)

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18 April 2020

review article

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title

The Role of Zinc and Zinc Homeostasis in Macrophage Function (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30622979%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

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12 October 2019

hemic and immune systems

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18 October 2019

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4 November 2019

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30622979%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

Lu Zhao

3

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18 April 2020

Junxia Min

4

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18 April 2020

Fudi Wang

5

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18 April 2020

author name string

Hong Gao

1

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18 April 2020

language of work or name

English

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publication date

6 December 2018

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12 October 2019

18 October 2019

4 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30622979%20AND%20SRC:MED&resulttype=core&format=json

Journal of Immunology Research

18 April 2020

published in

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12 October 2019

18 October 2019

4 November 2019

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18 April 2020

volume

2018

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18 April 2020

page(s)

6872621

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Creative Commons Attribution 4.0 International

18 April 2020

copyright license

3 references

12 October 2019

18 October 2019

Rates of metallothionein synthesis, degradation and accretion in a chicken macrophage cell line

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Functional significance of zinc-related signaling pathways in immune cells.

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Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells

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Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction

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Macrophage elastase kills bacteria within murine macrophages

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Metallothionein enhances angiogenesis and arteriogenesis by modulating smooth muscle cell and macrophage function

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Cellular zinc homeostasis is a regulator in monocyte differentiation of HL-60 cells by 1 alpha,25-dihydroxyvitamin D3.

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Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea

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A pilot study on zinc levels in patients with rheumatoid arthritis

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Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats

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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

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Detection of genomic changes in transgenic Bt rice populations through genetic fingerprinting using amplified fragment length polymorphism (AFLP).

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Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages

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12 December 2020

HIV-1 transgene expression in rats induces differential expression of tumor necrosis factor alpha and zinc transporters in the liver and the lung

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12 December 2020

Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT)-I/II null mutant mice

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12 December 2020

Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts

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12 December 2020

A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity

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12 December 2020

Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis

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12 December 2020

ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading

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12 December 2020

Repletion of zinc in zinc-deficient cells strongly up-regulates IL-1β-induced IL-2 production in T-cells.

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Chronic alcohol ingestion in rats decreases Krüppel-like factor 4 expression and intracellular zinc in the lung

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12 December 2020

Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response

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12 December 2020

Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia).

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12 December 2020

ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.

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The SLC30 family of zinc transporters - a review of current understanding of their biological and pathophysiological roles

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The SLC39 family of zinc transporters.

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12 December 2020

Macrophage biology in development, homeostasis and disease

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12 December 2020

Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet

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12 December 2020

Allosteric modulation of zinc speciation by fatty acids

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12 December 2020

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

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12 December 2020

ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

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12 December 2020

Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox- and Nrf2-independent manner.

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12 December 2020

Zinc signals and immune function

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12 December 2020

Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction

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12 December 2020

Differential regulation of TLR-dependent MyD88 and TRIF signaling pathways by free zinc ions.

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12 December 2020

Alveolar macrophage dysfunction and chronic alcohol use. Time to think about zinc

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12 December 2020

Functional studies of Drosophila zinc transporters reveal the mechanism for dietary zinc absorption and regulation

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12 December 2020

Granulocyte macrophage-colony stimulating factor induced Zn sequestration enhances macrophage superoxide and limits intracellular pathogen survival

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12 December 2020

The zinc transporter Zip5 (Slc39a5) regulates intestinal zinc excretion and protects the pancreas against zinc toxicity

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12 December 2020

Mechanism of uptake of ZnO nanoparticles and inflammatory responses in macrophages require PI3K mediated MAPKs signaling.

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12 December 2020

Zinc sequestration: arming phagocyte defense against fungal attack

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12 December 2020

[New therapies for rheumatoid arthritis]

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12 December 2020

Zinc depletion regulates the processing and secretion of IL-1β.

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12 December 2020

Toll-like receptor 6 mediated inflammatory and functional responses of zinc oxide nanoparticles primed macrophages

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12 December 2020

Topical application of zinc oxide nanoparticles reduces bacterial skin infection in mice and exhibits antibacterial activity by inducing oxidative stress response and cell membrane disintegration in macrophages

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12 December 2020

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

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12 December 2020

Zinc oxide nanoparticles impair bacterial clearance by macrophages.

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12 December 2020

Zinc oxide nanoparticles induce migration and adhesion of monocytes to endothelial cells and accelerate foam cell formation

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12 December 2020

Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles: a combined targeted and proteomic approach.

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12 December 2020

Differential impact of zinc deficiency on phagocytosis, oxidative burst, and production of pro-inflammatory cytokines by human monocytes.

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12 December 2020

Separation of zinc-dependent and zinc-independent events during early LPS-stimulated TLR4 signaling in macrophage cells

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Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages

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12 December 2020

Zinc homeostasis and immunosenescence.

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12 December 2020

Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development

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Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength

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12 December 2020

Macrophage iron homeostasis and polarization in the context of cancer

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12 December 2020

Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPD

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Elaidate, an 18-carbon trans-monoenoic fatty acid, but not physiological fatty acids increases intracellular Zn(2+) in human macrophages

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Zinc insufficiency mediates ethanol-induced alveolar macrophage dysfunction in the pregnant female mouse

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12 December 2020

Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation

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12 December 2020

Essential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation

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Serum Levels of Copper and Zinc in Patients with Rheumatoid Arthritis: a Meta-analysis.

1 reference

12 December 2020

Zinc- and oxidative property-dependent degradation of pro-caspase-1 and NLRP3 by ziram in mouse macrophages.

1 reference

12 December 2020

Pro-inflammatory responses of RAW264.7 macrophages when treated with ultralow concentrations of silver, titanium dioxide, and zinc oxide nanoparticles.

1 reference

12 December 2020

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

1 reference

12 December 2020

The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.

1 reference

12 December 2020

Zinc dyshomeostasis during polymicrobial sepsis in mice involves zinc transporter Zip14 and can be overcome by zinc supplementation

1 reference

12 December 2020

Combination of Zinc and All-Trans Retinoic Acid Promotes Protection against Listeria monocytogenes Infection

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12 December 2020

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

1 reference

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Autosomal-Recessive Intellectual Disability with Cerebellar Atrophy Syndrome Caused by Mutation of the Manganese and Zinc Transporter Gene SLC39A8.

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SLC39A8 Deficiency: A Disorder of Manganese Transport and Glycosylation

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Immunological orchestration of zinc homeostasis: The battle between host mechanisms and pathogen defenses

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Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia

1 reference

12 December 2020

IL-4 Induces Metallothionein 3- and SLC30A4-Dependent Increase in Intracellular Zn(2+) that Promotes Pathogen Persistence in Macrophages

1 reference

12 December 2020

Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

1 reference

12 December 2020

ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function

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12 December 2020

Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

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12 December 2020

Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival.

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1155/2018/6872621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30622979%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30622979%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

30622979

1 reference