Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease (Q61207151)

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13 February 2020

title

Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease (English)

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lysosomal storage disease

13 February 2020

main subject

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2

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13 February 2020

Daniel Kolarich

4

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13 February 2020

Nicki Packer

5

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13 February 2020

David J Vocadlo

7

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13 February 2020

Lorne Clarke

8

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13 February 2020

author name string

Xu He

1

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13 February 2020

Mark von Itzstein

3

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13 February 2020

Yi Qian

9

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13 February 2020

Tracey M Gloster

6

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13 February 2020

Allison R Kermode

10

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language of work or name

English

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publication date

1 January 2012

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13 February 2020

published in

Nature Communications

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volume

3

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issue

1

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page(s)

1062

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https://scigraph.springernature.com/pub.10.1038/ncomms2070

13 February 2020

exact match

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cites work

Influence of an ER-retention signal on the N-glycosylation of recombinant human α-L-iduronidase generated in seeds of Arabidopsis.

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N-glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans

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Optimal and consistent protein glycosylation in mammalian cell culture

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Mechanisms of subcellular mRNA localization

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Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

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Lysosomal disorders: from storage to cellular damage

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

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Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

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Guanidinylated neomycin mediates heparan sulfate-dependent transport of active enzymes to lysosomes

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Membrane anchors for vacuolar targeting: application in plant bioreactors

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Human alpha-L-iduronidase. 1. Purification, monoclonal antibody production, native and subunit molecular mass

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Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor

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As Genzyme flounders, competitors and activist investors swoop in.

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Structural studies of phosphorylated high mannose-type oligosaccharides

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Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies

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12 December 2020

Synthesis and deposition of zein in protein bodies of maize endosperm.

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12 December 2020

Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis

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A KDEL-tagged monoclonal antibody is efficiently retained in the endoplasmic reticulum in leaves, but is both partially secreted and sorted to protein storage vacuoles in seeds

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Protein storage bodies and vacuoles

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Improved virus neutralization by plant-produced anti-HIV antibodies with a homogeneous beta1,4-galactosylated N-glycan profile

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Criteria for high-level expression of a fungal laccase gene in transgenic maize

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Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis

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12 December 2020

Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase

1 reference

12 December 2020

Demonstration of the enzymatic mechanisms of α-N-acetyl-d-glucosamine-1-phosphodiester N-acetylglucosaminidase (formerly called α-N-acetylglucosaminylphosphodiesterase) and lysosomal α-N-acetylglucosaminidase

1 reference

12 December 2020

Uncleaved legumin in developing maize endosperm: identification, accumulation and putative subcellular localization

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12 December 2020

A genetic and structural analysis of the N-glycosylation capabilities

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12 December 2020

Structural requirements for efficient processing and activation of recombinant human UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase

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12 December 2020

Assembly of asparagine-linked oligosaccharides

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12 December 2020

Asymmetric localization of seed storage protein RNAs to distinct subdomains of the endoplasmic reticulum in developing maize endosperm cells

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12 December 2020

Alpha-L-iduronidase and enzyme replacement therapy for mucopolysaccharidosis I.

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Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy.

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N-Glycan analysis by matrix-assisted laser desorption/ionization mass spectrometry of electrophoretically separated nonmammalian proteins: application to peanut allergen Ara h 1 and olive pollen allergen Ole e 1.

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12 December 2020

Therapy for lysosomal storage disorders

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12 December 2020

Carbohydrate structures of recombinant human alpha-L-iduronidase secreted by Chinese hamster ovary cells

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12 December 2020

Function and glycosylation of plant-derived antiviral monoclonal antibody

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12 December 2020

Sequence analysis of a genomic clone encoding a Zc2 protein from Zea mays W64 A.

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12 December 2020

Plant-specific glycosylation patterns in the context of therapeutic protein production.

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12 December 2020

Clarifying lysosomal storage diseases

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12 December 2020

From planta to pharma with glycosylation in the toolbox.

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12 December 2020

Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues.

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The cellular pathology of lysosomal diseases

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12 December 2020

In planta protein sialylation through overexpression of the respective mammalian pathway

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Targeted drug delivery to bone: pharmacokinetic and pharmacological properties of acidic oligopeptide-tagged drugs

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From serendipity to therapy.

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12 December 2020

Human alpha-L-iduronidase: cDNA isolation and expression

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12 December 2020

mRNA localization in plants: targeting to the cell's cortical region and beyond.

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12 December 2020

Aptamer-based endocytosis of a lysosomal enzyme

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12 December 2020

Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans.

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12 December 2020

Sequential analysis of N- and O-linked glycosylation of 2D-PAGE separated glycoproteins

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12 December 2020

The mucopolysaccharidoses: a success of molecular medicine.

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS2070

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22990858%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 February 2020

ADS bibcode

2012NatCo...3.1062H

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