IQ motif selectivity in human IQGAP1: binding of myosin essential light chain and S100B (Q61781922)

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9 January 2020

title

IQ motif selectivity in human IQGAP1: binding of myosin essential light chain and S100B (English)

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9 January 2020

1

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9 January 2020

David J. Timson

7

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9 January 2020

author name string

Sara McSwiggen

3

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9 January 2020

Brett Greer

4

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9 January 2020

Pat Harriott

5

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9 January 2020

Sarah F Elliott

2

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9 January 2020

G Brent Irvine

6

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9 January 2020

publication date

28 June 2008

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Molecular and Cellular Biochemistry

9 January 2020

published in

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volume

318

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9 January 2020

issue

1-2

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9 January 2020

page(s)

43-51

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https://scigraph.springernature.com/pub.10.1007/s11010-008-9855-9

9 January 2020

exact match

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IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway

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IQGAP1 binds ERK2 and modulates its activity

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Identification of a human rasGAP-related protein containing calmodulin-binding motifs

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The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases

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Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications

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Binding of myosin essential light chain to the cytoskeleton-associated protein IQGAP1

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Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

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Ca2+-sensitive inactivation and facilitation of L-type Ca2+ channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in the(alpha)1C subunit

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Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

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IQGAP1 and calmodulin modulate E-cadherin function

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12 December 2020

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids

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Multiple sequence alignment with the Clustal series of programs

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The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin.

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IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

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Calcium negatively modulates calmodulin interaction with IQGAP1.

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The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function

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Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

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Identification of an IQGAP1/AKAP79 complex in beta-cells

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Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

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A logical sequence search for S100B target proteins

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The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes

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Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12

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IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

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Characterisation of two calmodulin-like proteins from the liver fluke, Fasciola hepatica

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12 December 2020

Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1

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Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis.

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12 December 2020

Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton

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12 December 2020

The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes

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12 December 2020

Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase

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12 December 2020

IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

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Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

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IQGAP1 binds Rap1 and modulates its activity

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Cloning and characterization of a novel transcript variant of IQGAP2 in human testis

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12 December 2020

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12 December 2020

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12 December 2020

Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase

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12 December 2020

Interaction of Moloney murine leukemia virus matrix protein with IQGAP

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12 December 2020

Cytokinesis: IQGAPs find a function

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Quantitation of putative activator-target affinities predicts transcriptional activating potentials

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