HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses (Q61799271)

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21 April 2020

title

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses (English)

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21 April 2020

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21 April 2020

Christian Hammer

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21 April 2020

Kristina M Herbert

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21 April 2020

Nikaïa Smith

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21 April 2020

Jacques Fellay

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21 April 2020

Daniel Sauter

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21 April 2020

author name string

Kristina Hopfensperger

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21 April 2020

Lukas Klein

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21 April 2020

Dominik Hotter

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21 April 2020

Paul D De Jesus

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21 April 2020

Lars Pache

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21 April 2020

Johannes A van der Merwe

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Sumit K Chanda

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Frank Kirchhoff

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language of work or name

English

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publication date

5 February 2019

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21 April 2020

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21 April 2020

volume

8

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describes a project that uses

21 April 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

DESeq2

object named as

DESeq2

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

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The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors

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HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

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Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

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HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency

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12 December 2020

Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein

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Cooperative contributions of interferon regulatory factor 1 (IRF1) and IRF8 to interferon-γ-mediated cytotoxic effects on oligodendroglial progenitor cells

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Next-generation sequencing reveals HIV-1-mediated suppression of T cell activation and RNA processing and regulation of noncoding RNA expression in a CD4+ T cell line

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12 December 2020

Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis

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12 December 2020

Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism

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Plasma IP-10 is associated with rapid disease progression in early HIV-1 infection

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HIV-1 Vpu does not degrade interferon regulatory factor 3.

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A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release

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IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

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Interleukin-6 and D-dimer levels at seroconversion as predictors of HIV-1 disease progression

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12 December 2020

Elevated IP10 levels are associated with immune activation and low CD4+ T-cell counts in HIV controller patients

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12 December 2020

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals

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12 December 2020

Tumor necrosis factor α is associated with viral control and early disease progression in patients with HIV type 1 infection

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12 December 2020

Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells

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12 December 2020

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12 December 2020

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12 December 2020

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins

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PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

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HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

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HIV-1 Vpu Mediates HLA-C Downregulation

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12 December 2020

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

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Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation

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12 December 2020

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

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Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.

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Identifiers

DOI

10.7554/ELIFE.41930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30717826%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

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21 April 2020

PubMed publication ID

30717826

1 reference