Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells (Q61876289)

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5 February 2020

title

Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells (English)

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5 February 2020

main subject

acute coronary syndrome

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7

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Dakang Xu

10

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author name string

Yingxia Zheng

1

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5 February 2020

Zhihao Wang

2

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5 February 2020

Lin Deng

3

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Xiangliang Yuan

4

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Yanhui Ma

5

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5 February 2020

Guanghui Zhang

6

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Jun-Ping Liu

8

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Lisong Shen

9

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language of work or name

English

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publication date

28 August 2012

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European Journal of Immunology

5 February 2020

published in

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volume

42

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issue

10

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page(s)

2803-2814

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Inflammation in atherosclerosis

5 February 2020

cites work

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Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

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The biological functions of T helper 17 cell effector cytokines in inflammation

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Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells

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Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells

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The Th17/Treg imbalance in patients with acute coronary syndrome

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Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

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Transforming growth factor-beta induces development of the T(H)17 lineage

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IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

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Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

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Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

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Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors

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7 January 2021

Osteopontin: role in immune regulation and stress responses

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7 January 2021

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques

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7 January 2021

Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis

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7 January 2021

Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions

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7 January 2021

Osteopontin Deficiency Attenuates Atherosclerosis in Female Apolipoprotein E–Deficient Mice

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7 January 2021

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

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7 January 2021

Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.

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7 January 2021

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis

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7 January 2021

Prognostic significance of plasma osteopontin levels in patients with chronic stable angina

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7 January 2021

CD4(+)CD25(+)CD127(low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression

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7 January 2021

Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner

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7 January 2021

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

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7 January 2021

Current views on the functions of interleukin-17A-producing cells in atherosclerosis

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7 January 2021

Novel role for osteopontin in cardiac fibrosis

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7 January 2021

Osteopontin: a fibrosis-related marker molecule in cardiac remodeling of enterovirus myocarditis in the susceptible host

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7 January 2021

Altered status of CD4(+)CD25(+) regulatory T cells in patients with acute coronary syndromes

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7 January 2021

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

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7 January 2021

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t.

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7 January 2021

IL-1beta and IL-2 convert human Treg into T(H)17 cells.

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Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

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7 January 2021

Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells

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7 January 2021

Identifiers

DOI

10.1002/EJI.201242475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22711477%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference