Overview of Current Therapeutics and Novel Candidates Against Influenza, Respiratory Syncytial Virus, and Middle East Respiratory Syndrome Coronavirus Infections (Q66679577)

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scientific article published in 2019

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English	Overview of Current Therapeutics and Novel Candidates Against Influenza, Respiratory Syncytial Virus, and Middle East Respiratory Syndrome Coronavirus Infections	scientific article published in 2019

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scholarly article

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Europe PubMed Central

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23 April 2020

1 reference

Europe PubMed Central

Overview of Current Therapeutics and Novel Candidates Against Influenza, Respiratory Syncytial Virus, and Middle East Respiratory Syndrome Coronavirus Infections (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31275265%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Respiratory syncytial virus

0 references

Middle East respiratory syndrome

1 reference

based on heuristic

inferred from title

Mohammad Amin Behzadi

1

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Europe PubMed Central

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23 April 2020

author name string

Victor H Leyva-Grado

2

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Europe PubMed Central

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23 April 2020

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publication date

19 June 2019

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Europe PubMed Central

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23 April 2020

Frontiers in Microbiology

1 reference

Europe PubMed Central

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23 April 2020

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Europe PubMed Central

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23 April 2020

1327

1 reference

Europe PubMed Central

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23 April 2020

copyright license

Creative Commons Attribution 4.0 International

19 June 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Quantitative Determination of Neuraminidase-Active Foci in Cell Monolayer Cultures Infected with Influenza or Newcastle Disease Virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of respiratory syncytial virus hospitalization among premature infants and infants with bronchopulmonary dysplasia using respiratory syncytial virus immune globulin prophylaxis. The PREVENT Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of respiratory syncytial virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recovery of cytopathogenic agent from chimpanzees with coryza

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of T-705 against influenza virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RSV604, a novel inhibitor of respiratory syncytial virus replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and mechanism of the M2 proton channel of influenza A virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of hospitalization due to respiratory syncytial virus: results from the Palivizumab Outcomes Registry

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolides: a new class of antiviral drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic monoclonal antibody treatment targeting respiratory syncytial virus (RSV) G protein mediates viral clearance and reduces the pathogenesis of RSV infection in BALB/c mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure and functional analysis of the influenza B proton channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the combination of favipiravir (T-705) and oseltamivir on influenza A virus infections in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre- and postexposure use of human monoclonal antibody against H5N1 and H1N1 influenza virus in mice: viable alternative to oseltamivir

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchiolitis: recent evidence on diagnosis and management

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influenza M2 proton channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics-Pharmacodynamics of a Respiratory Syncytial Virus Fusion Inhibitor in the Cotton Rat Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of respiratory syncytial virus preclinical and clinical variants resistant to neutralization by monoclonal antibodies palivizumab and/or motavizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly conserved neutralizing epitope on group 2 influenza A viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory tract infections: emerging viral pathogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory syncytial virus entry inhibitors targeting the F protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of H7N9 influenza A viruses isolated from humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus infections in health care workers

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory syncytial virus: virology, reverse genetics, and pathogenesis of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral susceptibility of variant influenza A(H3N2)v viruses isolated in the United States from 2011 to 2013

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigational antiviral drug, DAS181, effectively inhibits replication of zoonotic influenza A virus subtype H7N9 and protects mice from lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple immunoglobulin gene knockout transchromosomic cattle: bovine lambda cluster deletion and its effect on fully human polyclonal antibody production

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The global burden of respiratory disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: a preliminary report of two cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape due to host selection pressure

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and laboratory findings of the first imported case of Middle East respiratory syndrome coronavirus to the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of drug-resistant influenza A(H7N9) variants isolated from an oseltamivir-treated patient in Taiwan.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action for respiratory syncytial virus inhibitor RSV604.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a large cluster of influenza A(H1N1)pdm09 viruses cross-resistant to oseltamivir and peramivir during the 2013-2014 influenza season in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Palivizumab epitope-displaying virus-like particles protect rodents from RSV challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East Respiratory Syndrome - advancing the public health and research agenda on MERS - lessons from the South Korea outbreak

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of MERS-Coronavirus in Bactrian Camels, Southern Mongolia, November 2014.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2015 MERS outbreak in Korea: hospital-to-hospital transmission.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 1 clinical trials of DAS181, an inhaled sialidase, in healthy adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus (MERS-CoV): what lessons can we learn?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALN-RSV01 for prevention of bronchiolitis obliterans syndrome after respiratory syncytial virus infection in lung transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful treatment of avian-origin influenza A (H7N9) infection using convalescent plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy with lopinavir/ritonavir, ribavirin and interferon-α for Middle East respiratory syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism of respiratory syncytial virus fusion inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment strategies for Middle East respiratory syndrome coronavirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coronaviruses - drug discovery and therapeutic options.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peramivir: A Novel Intravenous Neuraminidase Inhibitor for Treatment of Acute Influenza Infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanobodies® as inhaled biotherapeutics for lung diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Studies To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody, MHAA4549A, in Healthy Volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-Influenza Treatment: Drugs Currently Used and Under Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A review of treatment modalities for Middle East Respiratory Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug candidates and model systems in respiratory syncytial virus antiviral drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Basis of Coronavirus Virulence and Vaccine Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory Syncytial Virus: Infection, Detection, and New Options for Prevention and Treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update on therapeutic options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, Tolerability, and Pharmacokinetics of MEDI8897, the Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody with an Extended Half-Life, in Healthy Adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influenza antivirals currently in late-phase clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral Treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome (MERS) coronavirus and dromedaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population Pharmacokinetic Modeling of JNJ-53718678, a Novel Fusion Inhibitor for the Treatment of Respiratory Syncytial Virus: Results from a Phase I, Double-Blind, Randomized, Placebo-Controlled First-in-Human Study in Healthy Adult Subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory syncytial virus: prospects for new and emerging therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cohort-study of patients suspected for MERS-CoV in a referral hospital in Saudi Arabia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MERS-coronavirus: From discovery to intervention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Hemagglutinin A Stem Antibody MEDI8852 Prevents and Controls Disease and Limits Transmission of Pandemic Influenza Viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of MHAA4549A, an Anti-Influenza A Monoclonal Antibody, in Healthy Subjects Challenged with Influenza A Virus in a Phase IIa Randomized Trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 2 Randomized Trial of the Safety and Efficacy of MHAA4549A, a Broadly Neutralizing Monoclonal Antibody, in a Human Influenza A Virus Challenge Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East respiratory syndrome coronavirus: five years later.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sofosbuvir-based Regimens in HIV/HCV Coinfected Patients after Liver Transplantation: Results from the ANRS CO23 CUPILT Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A review of candidate therapies for Middle East respiratory syndrome from a molecular perspective.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): A review

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Next Wave of Influenza Drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The susceptibility of circulating human influenza viruses to tizoxanide, the active metabolite of nitazoxanide

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiviral effects of RSV fusion inhibitor, MDT-637, on clinical isolates, versus its achievable concentrations in the human respiratory tract and comparison to ribavirin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RI-002, an intravenous immunoglobulin containing high titer neutralizing antibody to RSV and other respiratory viruses for use in primary immunodeficiency disease and other immune compromised populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human monoclonal antibodies as candidate therapeutics against emerging viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isosteric ribavirin analogues: Synthesis and antiviral activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zoonotic origin and transmission of Middle East respiratory syndrome coronavirus in the UAE.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNJ-63623872 treatment in adult volunteers experimentally inoculated with live influenza virus: a Phase IIa, randomized, double-blind, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, Tolerability, and Pharmacokinetics of MEDI8897, an Extended Half-Life Single-Dose Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing Variation in the Cost of Palivizumab for Respiratory Syncytial Virus Prevention in Preterm Infants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Universal Influenza Vaccine: The Strategic Plan for the National Institute of Allergy and Infectious Diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleosides for the treatment of respiratory RNA virus infections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Economic burden of seasonal influenza in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human respiratory syncytial virus: pathogenesis, immune responses, and current vaccine approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advancements in Host-Based Interventions for Influenza Treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of MEDI8852, an Anti-Influenza A Monoclonal Antibody, in Treating Acute Uncomplicated Influenza

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-exposure prophylaxis for Middle East respiratory syndrome in healthcare workers

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treating Influenza Infection, From Now and Into the Future

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility of Influenza Viruses to the Novel Cap-Dependent Endonuclease Inhibitor Baloxavir Marboxil

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New therapies for acute RSV infections: where are we?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31275265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FMICB.2019.01327

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31275265%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31275265%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31275265%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

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