Molecular evolution of the thermosensitive PAb1620 epitope of human p53 by DNA shuffling (Q72993916)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10488156%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Molecular evolution of the thermosensitive PAb1620 epitope of human p53 by DNA shuffling (English)

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31 October 2019

2

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31 October 2019

author name string

D P Xirodimas

series ordinal

1

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31 October 2019

language of work or name

English

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publication date

1 September 1999

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Journal of Biological Chemistry

31 October 2019

published in

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31 October 2019

volume

274

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31 October 2019

page(s)

28042-28049

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31 October 2019

issue

39

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

31 October 2019

cites work

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p53, the cellular gatekeeper for growth and division

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p53: puzzle and paradigm

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Cancer. p53, guardian of the genome

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A death in the life of p53

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Presence of a potent transcription activating sequence in the p53 protein

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Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

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Mammalian p53 can function as a transcription factor in yeast

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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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Interaction of p53 with its consensus DNA-binding site

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Regulation of the specific DNA binding function of p53

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Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

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p53 mutations in human cancers

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p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers

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Mutations in the p53 gene occur in diverse human tumour types

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

21 January 2018

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Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group

21 January 2018

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Regulation of mutant p53 temperature-sensitive DNA binding.

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Thermodynamic stability of wild-type and mutant p53 core domain

21 January 2018

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Rapid evolution of a protein in vitro by DNA shuffling

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DNA shuffling brightens prospects for GFP.

21 January 2018

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DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

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Improved green fluorescent protein by molecular evolution using DNA shuffling.

21 January 2018

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Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening

21 January 2018

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Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions.

21 January 2018

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Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression.

21 January 2018

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Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library

21 January 2018

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A simple and rapid method for generating a deletion by PCR

21 January 2018

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Specific p53-DNA complexes contain an mdm2-related protein

21 January 2018

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Mdm2 promotes the rapid degradation of p53

21 January 2018

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Regulation of p53 stability by Mdm2

21 January 2018

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Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

21 January 2018

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Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.

21 January 2018

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Molecular evolution of an arsenate detoxification pathway by DNA shuffling.

21 January 2018

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The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability

21 January 2018

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Primary structure polymorphism at amino acid residue 72 of human p53.

21 January 2018

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Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.

21 January 2018

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Identification of an allosteric binding site on the transcription factor p53 using a phage-displayed peptide library

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Apoptosis in cancer therapy: crossing the threshold

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Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

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21 January 2018

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Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

21 January 2018

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Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.39.28042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10488156%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference