Differential mechanisms of cytochrome P450 inhibition and activation by alpha-naphthoflavone (Q73025189)

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31 October 2019

title

Differential mechanisms of cytochrome P450 inhibition and activation by alpha-naphthoflavone (English)

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31 October 2019

2

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author name string

A P Koley

1

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31 October 2019

R C Robinson

3

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A Markowitz

4

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31 October 2019

F K Friedman

5

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31 October 2019

language of work or name

English

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publication date

1 February 1997

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Journal of Biological Chemistry

31 October 2019

number of pages

4

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based on heuristic

inferred from page(s)

published in

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31 October 2019

volume

272

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31 October 2019

issue

6

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page(s)

3149-3152

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Role of chemopreventers in human diet

31 October 2019

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Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids

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Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers

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Inhibition of ethoxy- and pentoxy-resorufin dealkylases of rat liver by flavones and flavonols: structure-activity relationship

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Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids.

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Alpha-Naphthoflavone: An Inhibitor of Hydrocarbon Cytotoxicity and Microsomal Hydroxylase

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Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

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Aryl Hydrocarbon Hydroxylase and Polycyclic Hydrocarbon Tumorigenesis: Effect of the Enzyme Inhibitor 7,8-Benzoflavone on Tumorigenesis and Macromolecule Binding

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The human hepatic cytochromes P450 involved in drug metabolism

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Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

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A preliminary structure-activity study of the mixed-function oxidase inhibitor, 7,8-benzoflavone

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Propofol for sedation and control of intracranial pressure in children.

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Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes

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Activation of monooxygenases in human liver by 7,8-benzoflavone

21 January 2018

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Analysis of relaxation processes helps to define molecular states in biological systems

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Kinetics of CO binding to cytochromes P450 in the endoplasmic reticulum

21 January 2018

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Interaction of polycyclic aromatic hydrocarbons and flavones with cytochromes P450 in the endoplasmic reticulum: effect on CO binding kinetics

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CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.

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Agonist-receptor efficacy. I: Mechanisms of efficacy and receptor promiscuity.

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Conformational induction versus conformational selection: evidence from allosteric enhancers

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Identifiers

DOI

10.1074/JBC.272.6.3149

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31 October 2019

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